Spinocerebellar ataxias (SCAs) represent a large group of hereditary degenerative diseases
of the nervous system, in particular the cerebellum, and other systems that manifest with a …

Despite a growing proportion of aged individuals at risk for developing cancer in the brain,
the prognosis for these conditions remains abnormally poor due to limited knowledge of …

Gene expression alterations occurring with aging have been described for a multitude of
species, organs, and cell types. However, most of the underlying studies rely on static …

Background and Purpose: Age is identified as a significant prognostic factor for poorer
outcome after stroke. However, environmental enrichment (EE) has been reported to …

Background The increasing age of global populations highlights the urgent need to
understand the biological underpinnings of ageing. To this end, inhibition of the …

Astrocytes, a major class of glial cells, are an important element at the synapse where they
engage in bidirectional crosstalk with neurons to regulate numerous aspects of …

Astrocytes have gained increasing recognition as key elements of a broad array of nervous
system functions. These include essential roles in synapse formation and elimination …