Peptides are distinctive biomacromolecules that demonstrate potential cytotoxicity and
diversified bioactivities against a variety of microorganisms including bacteria, mycobacteria …

BCS class II drugs pose challenging problems in their pharmaceutical product development
process because of their low solubility and dissolution rates. They require enhancement in …

Some drugs have low bioavailability due to their poor aqueous solubility and/or slow
dissolution rate in biological fluids. Stiripentol (STP) is a novel anticonvulsant drug that is …

Purpose: The aim of the present work was to improve rate of dissolution and processing
parameters of BCS class II drug, chlorzoxazone using cogrinding technique in the presence …

Cocrystallization of drugs in presence of excipients can become an effective tool to improve
physicochemical and mechanical properties of drugs which may ultimately affect its …

The aim of this study was to develop Aceclofenac solid dispersion (ACSD) formulation using
different types of carriers. Aceclofenac is class II BCS which mean high permeability …

ABSTRACT Objective: An ODTs development requires the incorporation of highly soluble
drugs to achieve the intended effect. In a challenge to prepare ODT of Aceclofenac, its solid …

The aim of this work was to improve the mechanical properties of Metformin HCl by its
recrystallization in the presence of different polymers and excipients using a wide range of …

The aim of present work was to improve physicochemical properties of model drug
Chlorzoxazone by crystallo-co-agglomeration (CCA) in the presence of different polymers …

Аннотация В статье представлен краткий обзор применения твердых дисперсий
нестероидных противовоспалительных средств с полимерными носителями. Твердые …