Glutathione (GSH), a tripeptide particularly concentrated in the liver, is the most important
thiol reducing agent involved in the modulation of redox processes. It has also been …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Apoptosis, also known as programmed cell death is a highly regulated and crucial process
found in all multicellular organisms. It is not only implicated in regulatory mechanisms of …

The field of medicinal inorganic chemistry has evolved with three conceptual aims: the
introduction of metal ions to the biological system, manipulation and redistribution of metal …

The most reliable and robust risk factor for some neurodegenerative diseases is aging. It has
been proposed that processes of aging are associated with the generation of reactive …

Significance: Eryptosis, the suicidal erythrocyte death, is characterized by cell shrinkage,
membrane blebbing, and phosphatidylserine translocation to the outer membrane leaflet …

Glutathione (GSH) is the most abundant cellular tripeptide (L‐γ‐glutamate‐L‐cysteinyl‐
glycine) which is as critical as oxygen and water. This low molecular mass antioxidant has a …

The locus coeruleus is a pontine nucleus that produces much of the brain's norepinephrine.
Despite its small size, the locus coeruleus is critical for a myriad of functions and is involved …

Thiols are the organic compounds that contain a sulphydryl group. Among all the
antioxidants that are available in the body, thiols constitute the major portion of the total body …

Copper (Cu) at a higher level becomes toxic and it can catalyze the formation of highly
reactive hydroxyl radical. We report the vulnerability of liver, kidney and brain to different …