Due to the three domains of the colchicine-site which is conducive to the combination with
small molecule compounds, colchicine-site on the tubulin has become a common target for …

Ovarian cancer is among the most lethal gynecologic malignancies with a poor survival
prognosis. The current therapeutic strategies involve surgery and chemotherapy. Research …

Antimitotics are important anticancer agents and include the natural alkaloid prodrug
colchicine (COL). However, a major challenge of using COL as an anticancer drug is its …

An ecofriendly, magnetically retrievable amine-functionalized SiO2@ Fe3O4 catalyst was
successfully synthesized and affirmed by several physicochemical characterization tools …

In the present study, mesalamine-functionalized on magnetic nanoparticles
(mesalamine/GPTMS@ SiO2@ Fe3O4) is fabricated as an efficient and magnetically …

In this research, we successfully designed and synthesized a new core-shell-structured
inorganic-organic hybrid magnetic nanocatalyst via the ethylene diamine immobilized to the …

Triple-negative breast cancer (TNBC) accounts for approximately 15% of breast cancer
cases in the United States. TNBC has poorer overall prognosis relative to other molecular …

Five new series of pyrrolo-fused heterocycles were designed through a scaffold
hybridization strategy as analogs of the well-known microtubule inhibitor phenstatin …

Background Breast cancer (BC) is a common malignant tumor with poor prognosis.
Angiogenesis is related to the growth and progression of solid tumors and associated with …

In this study, we synthesized the GPTMS‐guanidine attached to the magnetic nanoparticles
(Fe3O4@ SiO2@ GPTMS@ guanidine) as a novel and efficient heterogeneous nanocatalyst …