Biochemical Functions of Coenzyme Q10

FL Crane - Journal of the American College of Nutrition, 2001 - Taylor & Francis
Coenzyme Q is well defined as a crucial component of the oxidative phosphorylation
process in mitochondria which converts the energy in carbohydrates and fatty acids into ATP …

Bioenergetic and Antioxidant Properties of Coenzyme Q10: Recent Developments

GP Littarru, L Tiano - Molecular biotechnology, 2007 - Springer
For a number of years, coenzyme Q (CoQ 10 in humans) was known for its key role in
mitochondrial bioenergetics; later studies demonstrated its presence in other subcellular …

Mitochondrial medicine–molecular pathology of defective oxidative phosphorylation

E Fosslien - Annals of Clinical & Laboratory Science, 2001 - Assoc Clin Scientists
Different tissues display distinct sensitivities to defective mitochondrial oxidative
phosphorylation (OXPHOS). Tissues highly dependent on oxygen such as the cardiac …

Coenzyme q10 and statin-induced mitochondrial dysfunction

R Deichmann, C Lavie, S Andrews - Ochsner Journal, 2010 - ochsnerjournal.org
Coenzyme Q10 is an important factor in mitochondrial respiration. Primary and secondary
deficiencies of coenzyme Q10 result in a number of neurologic and myopathic syndromes …

Coenzyme Q10: From bench to clinic in aging diseases, a translational review

FM Gutierrez-Mariscal… - Critical reviews in …, 2019 - Taylor & Francis
ABSTRACT Coenzyme Q10 (CoQ10) is a ubiquitous molecule present in all eukaryotic
organisms whose principal role in the cell is related to its participation in the electron …

The clinical use of HMG CoA‐reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications

PH Langsjoen, AM Langsjoen - Biofactors, 2003 - Wiley Online Library
The depletion of the essential nutrient CoQ10 by the increasingly popular cholesterol
lowering drugs, HMG CoA reductase inhibitors (statins), has grown from a level of concern to …

Oxidative stress in surgery in an ageing population: pathophysiology and therapy

F Rosenfeldt, M Wilson, G Lee, C Kure, R Ou… - Experimental …, 2013 - Elsevier
Reactive oxygen species (ROS) play an important role in the regulation of normal cellular
function. When ROS are produced in excess they can have detrimental effects, a state …

[HTML][HTML] Coenzyme Q10 therapy before cardiac surgery improves mitochondrial function and in vitro contractility of myocardial tissue

F Rosenfeldt, S Marasco, W Lyon, M Wowk… - The Journal of Thoracic …, 2005 - Elsevier
OBJECTIVES: Previous clinical trials suggest that coenzyme Q10 might afford myocardial
protection during cardiac surgery. We sought to measure the effect of coenzyme Q10 …

Cardiovascular complications of non-steroidal anti-inflammatory drugs

E Fosslien - Annals of Clinical & Laboratory Science, 2005 - Assoc Clin Scientists
Coxibs, such as rofecoxib, celecoxib, and valdecoxib, selectively inhibit cyclooxygenase
(COX)-2, the mainly inducible, pro-inflammatory COX isoform. Unlike traditional non …

Reduction of ascites mortality in broilers by coenzyme Q10

AL Geng, YM Guo, Y Yang - Poultry Science, 2004 - Elsevier
Abstract Effects of coenzyme Q 10 (CoQ 10) supplementation on growth performance and
ascites were studied in broilers. One hundred eighty 1-d-old Arbor Acre male broiler chicks …