The framework of transition path theory (TPT) is developed in the context of continuous-time
Markov chains on discrete state-spaces. Under assumption of ergodicity, TPT singles out …

NaChBac was the first discovered bacterial sodium voltage-dependent channel, yet
computational studies are still limited due to the lack of a crystal structure. In this work, a …

Virtual machine distributed computing greatly simplifies the use of widespread computing
resources by lowering the level of abstraction, benefiting both resource providers and users …

Modern Infrastructure-as-a-Service (IaaS) clouds offer an unprecedented flexibility and
elasticity in terms of resource provisioning through the use of hardware virtualization …

Constructing Markov state models from large-scale molecular dynamics simulation
trajectories is a promising approach to dissect the kinetic mechanisms of complex chemical …

Transition events in complex systems between long lived states are a key feature of many
systems arising in physics, chemistry, biology, etc. It was early recognized that transition …

Optical networking may dramatically change high performance distributed computing. One
reason is that optical networks can support provisioning dynamically configurable lightpaths …

A virtual execution environment consisting of virtual machines (VMs) interconnected with
virtual networks provides opportunities to dynamically optimize, at run-time, the performance …

Hollow polyhedral cages hold great potential for application in nanotechnological and
biomedical fields. Understanding the formation mechanism of these self-assembled …

Abstract Moving Target Defense (MTD) was proposed as a promising defense paradigm to
introduce various uncertainties into computer systems, which can greatly raise the bar for the …