Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

Acute and chronic kidney disease encompasses a complex set of diseases that can both
lead to, and result from, cancer. In particular, kidney disease can arise from the use of …

Short‐term outcomes in kidney transplantation are marred by progressive transplant failure
and mortality secondary to immunosuppression toxicity. Immune modulation with autologous …

Tumours exhibit notable metabolic alterations compared with their corresponding normal
tissue counterparts. These metabolic alterations can support anabolic growth, enable …

Importance Among kidney transplant recipients, Black patients continue to have worse graft
function and reduced patient and graft survival. Better understanding of different phenotypes …

Cancer is a significant cause of morbidity and mortality after solid organ transplantation
(SOT) and related to lifelong immunosuppression. This retrospective registry study assessed …

Kidney transplant recipients are at particular risk for developing tumors, many of which are
now routinely treated with immune checkpoint inhibitors (ICIs); however, ICI therapy can …

Since the late 19th century, the immune system has increasingly garnered interest as a
novel avenue for cancer therapy, particularly given scientific breakthroughs in recent …

The pattern of delayed recurrence in a subset of breast cancer patients has long been
explained by a model that incorporates a variable period of cellular or tumor mass dormancy …

The immunosuppressive agent mycophenolate is used extensively in kidney transplantation,
yet dosing strategy applied varies markedly from fixed dosing (“one-dose-fits-all”), to …