TFEB and TFE3: linking lysosomes to cellular adaptation to stress
N Raben, R Puertollano - Annual review of cell and …, 2016 - annualreviews.org
In recent years, our vision of lysosomes has drastically changed. Formerly considered to be
mere degradative compartments, they are now recognized as key players in many cellular …
mere degradative compartments, they are now recognized as key players in many cellular …
The lysosome as a command-and-control center for cellular metabolism
Lysosomes are membrane-bound organelles found in every eukaryotic cell. They are widely
known as terminal catabolic stations that rid cells of waste products and scavenge metabolic …
known as terminal catabolic stations that rid cells of waste products and scavenge metabolic …
Proteogenomic characterization of MiT family translocation renal cell carcinoma
Y Qu, X Wu, A Anwaier, J Feng, W Xu, X Pei… - Nature …, 2022 - nature.com
Microphthalmia transcription factor (MiT) family translocation renal cell carcinoma (tRCC) is
a rare type of kidney cancer, which is not well characterized. Here we show the …
a rare type of kidney cancer, which is not well characterized. Here we show the …
Computational analysis of pathological images enables a better diagnosis of TFE3 Xp11. 2 translocation renal cell carcinoma
Abstract TFE3 Xp11. 2 translocation renal cell carcinoma (TFE3-RCC) generally progresses
more aggressively compared with other RCC subtypes, but it is challenging to diagnose …
more aggressively compared with other RCC subtypes, but it is challenging to diagnose …
Incidence, clinicopathological features and fusion transcript landscape of translocation renal cell carcinomas
Aims Translocation renal cell carcinoma (tRCC) is a rare subtype of kidney tumour
characterized by translocations involving the transcription factor TFE 3 or TFEB. tRCC was …
characterized by translocations involving the transcription factor TFE 3 or TFEB. tRCC was …
Morphologic, molecular, and taxonomic evolution of renal cell carcinoma: a conceptual perspective with emphasis on updates to the 2016 World Health Organization …
AM Udager, R Mehra - Archives of Pathology & Laboratory …, 2016 - meridian.allenpress.com
Molecular and morphologic interrogation has driven a much-needed reexamination of renal
cell carcinoma (RCC). Indeed, the recently released 2016 World Health Organization …
cell carcinoma (RCC). Indeed, the recently released 2016 World Health Organization …
Comprehensive genomic analysis of translocation renal cell carcinoma reveals copy-number variations as drivers of disease progression
Purpose: Translocation renal cell carcinoma (tRCC) is a rare, aggressive renal cell
carcinoma (RCC) subtype. There is currently limited understanding on the role of molecular …
carcinoma (RCC) subtype. There is currently limited understanding on the role of molecular …
Comprehensive immunoprofiles of renal cell carcinoma subtypes
M Kim, JW Joo, SJ Lee, YA Cho, CK Park, NH Cho - Cancers, 2020 - mdpi.com
In recent years, renal epithelial tumors have been among the fastest reclassifying tumors,
requiring updates to the tumor classification system. Nonetheless, immunohistochemistry …
requiring updates to the tumor classification system. Nonetheless, immunohistochemistry …
Renal tumors of childhood—a histopathologic pattern-based diagnostic approach
AHAG Ooms, GM Vujanić, E D'hooghe, P Collini… - Cancers, 2020 - mdpi.com
Renal tumors comprise approximately 7% of all malignant pediatric tumors. This is a highly
heterogeneous group of tumors, each with its own therapeutic management, outcome, and …
heterogeneous group of tumors, each with its own therapeutic management, outcome, and …
TRIM63 is a sensitive and specific biomarker for MiT family aberration-associated renal cell carcinoma
Microphthalmia-associated transcription factor (MiT) family aberration-associated renal cell
carcinoma (MiTF-RCC) is a subtype of renal cell carcinoma harboring recurrent …
carcinoma (MiTF-RCC) is a subtype of renal cell carcinoma harboring recurrent …