Cardiovascular malformations are the most common type of birth defect and result in
significant mortality worldwide. The etiology for the majority of these anomalies remains …

Congenital heart disease (CHD) occurs in∼ 1% of newborns. CHD arises from many distinct
etiologies, ranging from genetic or genomic variation to exposure to teratogens, which elicit …

Clinically relevant congenital heart disease affects 1% of all live births. It is the leading
cause of birth defects–related death in the United States, claiming more than 6000 lives per …

Congenital cardiac abnormalities are, due to their relatively high frequency and severe
impact on quality of life, an important focus in cardiovascular research. Recently, various …

Low birth weight (LBW) infants have increased susceptibility to perinatal complications. An
immature and impaired vascular system may possibly participate in these complications …

The aim of the study was to assess the association between bronchopulmonary dysplasia
(BPD) and polymorphisms of genes coding for vascular endothelial growth factor (VEGF) …

Background Normal growth and development of organisms requires maintenance of a
dynamic balance between systems that promote cell survival and those that induce …

The importance of vascular endothelial growth factor-A (VEGF) and subsequent Notch
signaling in cardiac outflow tract development is generally recognized. Although genetic …

The endothelium of the cardiac valves is unique compared the rest of the vasculature in its
ability to undergo an endothelial-to-mesenchymal transformation (EMT) in vitro in response …

Objective. To determine whether variants in the vascular endothelial growth factor A
(VEGFA) gene are associated with ischemic heart disease (IHD) and/or myocardial …