Defining the cellular target (s) of porcine reproductive and respiratory syndrome virus blocking monoclonal antibody 7G10

JK Kim, AM Fahad, K Shanmukhappa… - Journal of virology, 2006 - Am Soc Microbiol
We produced a monoclonal antibody (MAb)(7G10) that has blocking activity against porcine
reproductive and respiratory syndrome virus (PRRSV). In this study, we identified the …

Human cytomegalovirus infection dysregulates the canonical Wnt/β-catenin signaling pathway

M Angelova, K Zwezdaryk, MB Ferris, B Shan… - 2012 - journals.plos.org
Human Cytomegalovirus (HCMV) is a ubiquitous herpesvirus that currently infects a large
percentage of the world population. Although usually asymptomatic in healthy individuals …

Onset of human cytomegalovirus replication in fibroblasts requires the presence of an intact vimentin cytoskeleton

MS Miller, L Hertel - Journal of virology, 2009 - Am Soc Microbiol
Like all viruses, herpesviruses extensively interact with the host cytoskeleton during entry.
While microtubules and microfilaments appear to facilitate viral capsid transport toward the …

Herpesviruses and intermediate filaments: close encounters with the third type

L Hertel - Viruses, 2011 - pmc.ncbi.nlm.nih.gov
Intermediate filaments (IF) are essential to maintain cellular and nuclear integrity and shape,
to manage organelle distribution and motility, to control the trafficking and pH of intracellular …

RhoB is a component of the human cytomegalovirus assembly complex and is required for efficient viral production

N Goulidaki, S Alarifi, SH Alkahtani, A Al-Qahtani… - Cell Cycle, 2015 - Taylor & Francis
Human Cytomegalovirus (HCMV), an ubiquitous β-herpesvirus, is a significant pathogen
that causes medically severe diseases in immunocompromised individuals and in …

Global analysis of ubiquitome in PRRSV-infected pulmonary alveolar macrophages

H Zhang, L Fang, X Zhu, D Wang, S Xiao - Journal of proteomics, 2018 - Elsevier
Protein lysine ubiquitination is a dynamic reversible post-translational modification that plays
key roles in modulating different cellular processes. Porcine reproductive and respiratory …

Pseudorabies virus US3 leads to filamentous actin disassembly and contributes to viral genome delivery to the nucleus

T Jacob, C Van den Broeke, K Grauwet, K Baert… - Veterinary …, 2015 - Elsevier
The conserved alphaherpesvirus US3 tegument protein induces rearrangements of the actin
cytoskeleton, consisting of protrusion formation and stress fiber breakdown. Although US3 …

[HTML][HTML] Sequestration of human cytomegalovirus by human renal and mammary epithelial cells

N Twite, G Andrei, C Kummert, C Donner… - Virology, 2014 - Elsevier
Urine and breast milk represent the main routes of human cytomegalovirus (HCMV)
transmission but the contribution of renal and mammary epithelial cells to viral excretion …

Varicella-zoster virus infection influences expression and organization of actin and α-tubulin but does not affect lamin A and vimentin

M Kuhn, N Desloges, M Rahaus, MH Wolff - Intervirology, 2005 - karger.com
Objective: The aim of this study was to examine the effects of varicella-zoster virus (VZV)
infection on the cytoskeletal components actin, lamin A, α-tubulin and vimentin. Methods …

Proteasomes raise the microtubule dynamics in influenza A (H1N1) virus-infected LLC-MK2 cells

FD Conto, C Chezzi, A Fazzi, SV Razin… - Cellular and Molecular …, 2015 - degruyter.com
The dynamics of microtubule networks are known to have an impact on replication of
influenza A virus in some cellular models. Here we present evidence suggesting that at late …