Background: Neurological disorders are composed of several diseases that affect the central
and peripheral nervous system; among these are neurodegenerative diseases, which lead …

Background Parkinson's disease (PD) is the second most common neurodegenerative
disease with a significant public health burden. It is characterized by the gradual …

There is a paucity of genetic characterization in people with Parkinson's disease (PD) of
Latino and Afro-Caribbean descent. Screening LRRK2 and GBA variants in 32 New Yorkers …

Introduction Parkinson's disease is a chronic neurodegenerative multisystemic disorder that
affects approximately 2% of the population over 65 years old. This disorder is characterized …

Major depressive disorder (MDD) and other psychiatric conditions are debilitating illnesses
affecting millions globally. Catechol-O-methyltransferase (COMT), an enzyme that regulates …

Parkinson's disease (PD) is a chronic neurodegenerative disorder (ND) characterised by
gradual degradation of dopaminergic neurons in the substantia nigra pars compacta (SNpc) …

Increasing the prevalence of Parkinson's disease is an alarming sign that needs attention,
so focusing on new medications and regimens which play an important role in prevention …

Parkinson's disease is a degenerative nervous system disorder caused by the death of
dopamine-producing cells in the substantia nigra. Dopaminergic treatment could alleviate …

The expression and activity of ionotropic glutamate receptors control signal transduction at
the excitatory synapses in the central nervous system. The major class are the calcium …

Precision medicine is an emerging medical approach which aims to individualize therapies
in patients with complex, multifactorial disease in order to increase drug effectiveness and …