Polysaccharide nanoparticles: From fabrication to applications

A Plucinski, Z Lyu, BVKJ Schmidt - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Polysaccharides have attracted considerable attention in a broad range of applications in
recent years, which is due to their remarkable features such as biocompatibility …

Emerging aqueous two-phase systems: from fundamentals of interfaces to biomedical applications

Y Chao, HC Shum - Chemical Society Reviews, 2020 - pubs.rsc.org
Aqueous two-phase systems (ATPSs) have been recognized for their applications in
extraction, separation, purification, and enrichment of (bio) molecules and cells. Recently …

Multiphase complex coacervate droplets

T Lu, E Spruijt - Journal of the American Chemical Society, 2020 - ACS Publications
Liquid–liquid phase separation plays an important role in cellular organization. Many
subcellular condensed bodies are hierarchically organized into multiple coexisting domains …

Phase-separation facilitated one-step fabrication of multiscale heterogeneous two-aqueous-phase gel

F Chen, X Li, Y Yu, Q Li, H Lin, L Xu… - Nature …, 2023 - nature.com
Engineering heterogeneous hydrogels with distinct phases at various lengths, which
resemble biological tissues with high complexity, remains challenging by existing fabricating …

Biomolecular chemistry in liquid phase separated compartments

KK Nakashima, MA Vibhute, E Spruijt - Frontiers in molecular …, 2019 - frontiersin.org
Biochemical processes inside the cell take place in a complex environment that is highly
crowded, heterogeneous, and replete with interfaces. The recently recognized importance of …

[HTML][HTML] Hydrophilic polymers: Current trends and visions for the future

N Bayliss, BVKJ Schmidt - Progress in Polymer Science, 2023 - Elsevier
Hydrophilic polymers are a major class of polymers in polymer science. They are found in
broad range of applications from superabsorbers to drug-delivery. In recent years, a plethora …

Cell‐inspired all‐aqueous microfluidics: from intracellular liquid–liquid phase separation toward advanced biomaterials

Q Ma, Y Song, W Sun, J Cao, H Yuan… - Advanced …, 2020 - Wiley Online Library
Living cells have evolved over billions of years to develop structural and functional
complexity with numerous intracellular compartments that are formed due to liquid–liquid …

Martini 3 coarse-grained force field for carbohydrates

F Grünewald, MH Punt, EE Jefferys… - Journal of Chemical …, 2022 - ACS Publications
The Martini 3 force field is a full reparametrization of the Martini coarse-grained model for
biomolecular simulations. Due to the improved interaction balance, it allows for a more …

Formation of multiphase complex coacervates and partitioning of biomolecules within them

GA Mountain, CD Keating - Biomacromolecules, 2019 - ACS Publications
Biological systems employ liquid–liquid phase separation to localize macromolecules and
processes. The properties of intracellular condensates that allow for multiple, distinct liquid …

Freeform, reconfigurable embedded printing of all‐aqueous 3D architectures

G Luo, Y Yu, Y Yuan, X Chen, Z Liu… - Advanced …, 2019 - Wiley Online Library
Aqueous microstructures are challenging to create, handle, and preserve since their
surfaces tend to shrink into spherical shapes with minimum surface areas. The creation of …