Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

Engineered nanomaterial uptake and tissue distribution: from cell to organism

H Kettiger, A Schipanski, P Wick… - International journal of …, 2013 - Taylor & Francis
Improved understanding of interactions between nanoparticles and biological systems is
needed to develop safety standards and to design new generations of nanomaterials. This …

In-vitro in-vivo correlation (IVIVC) in nanomedicine: Is protein corona the missing link?

P Jain, RS Pawar, RS Pandey, J Madan, S Pawar… - Biotechnology …, 2017 - Elsevier
One of the unmet challenges in nanotechnology is to understand and establish the
relationship between physicochemical properties of nanoparticles (NPs) and its biological …

Genetically engineered protein corona‐based cascade nanozymes for enhanced tumor therapy

Z Liu, Q Liu, H Zhang, X Zhang, J Wu… - Advanced Functional …, 2022 - Wiley Online Library
The emergence of nanomedicine has provided a promising strategy to greatly enhance the
therapeutic efficacy of O2‐dependent photodynamic therapy (PDT). However, plasma …

Immunotoxicity considerations for next generation cancer nanomedicines

G Hannon, J Lysaght, NJ Liptrott… - Advanced …, 2019 - Wiley Online Library
Although interest and funding in nanotechnology for oncological applications is thriving,
translating these novel therapeutics through the earliest stages of preclinical assessment …

Effect of silica-based mesoporous nanomaterials on human blood cells

SP Fortis, A Batrinou, HT Georgatzakou… - Chemico-Biological …, 2024 - Elsevier
Different mesoporous nanomaterials (MSNs) are constantly being developed for a range of
therapeutic purposes, but they invariably interact with blood components and may cause …

Formation and biological effects of protein corona for food‐related nanoparticles

G Cui, W Su, M Tan - … Reviews in Food Science and Food …, 2022 - Wiley Online Library
The rapid development of nanoscience and nanoengineering provides new perspectives on
the composition of food materials, and has great potential for food biology research and …

Current advances in nanomaterials affecting morphology, structure, and function of erythrocytes

Y Tian, Z Tian, Y Dong, X Wang, L Zhan - RSC advances, 2021 - pubs.rsc.org
In recent decades, nanomaterials have been widely used in the field of biomedicine due to
their unique physical and chemical properties, and have shown good prospects for in vitro …

Amine-functionalized SiO2 nanodot-coated layered double hydroxide nanocomposites for enhanced gene delivery

L Li, W Gu, J Liu, S Yan, ZP Xu - Nano Research, 2015 - Springer
In this work a novel strategy has been developed to prepare well-dispersed amine-
functionalized SiO 2 nanodot-coated layered double hydroxide nanocomposite (NH 2-SiO …

Strategies to optimize the biocompatibility of iron oxide nanoparticles–“SPIONs safe by design”

C Janko, J Zaloga, M Pöttler, S Dürr, D Eberbeck… - Journal of Magnetism …, 2017 - Elsevier
Various nanoparticle systems have been developed for medical applications in recent years.
For constant improvement of efficacy and safety of nanoparticles, a close interdisciplinary …