Adolescence is a developmental period when physical and cognitive abilities are optimized,
when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal …

In the young of many mammalian species, including humans, a vigorous and highly
rewarding social activity is abundantly expressed, known as social play behaviour. Social …

Adolescence is an evolutionarily conserved developmental phase characterized by
hormonal, physiological, neural and behavioral alterations evident widely across …

The brain is one of the major target organs of alcohol actions. Alcohol abuse can lead to
alterations in brain structure and functions and, in some cases, to neurodegeneration …

The adolescent transition is associated with increases in reward-and sensation-seeking,
peer-directed social interactions, and risk-taking, with exploratory use of alcohol and other …

Background: Adolescents with alcohol use disorders (AUD) have shown smaller prefrontal
cortex (PFC) volumes compared with healthy controls; however, differences may have been …

Alcohol can permeate virtually every organ and tissue in the body, resulting in tissue injury
and organ dysfunction. Considerable evidence indicates that alcohol abuse results in …

BACKGROUND: Converging lines of evidence suggest that the hippocampus may be
particularly vulnerable to deleterious effects of alcohol and marijuana use, especially during …

Adolescence is associated with potentially stressful challenges, and adolescents may differ
from adults in their stress responsivity. To investigate possible age-related differences in …

Interactions with peers become particularly important during adolescence, and age
differences in social interactions have been successfully modeled in rats. To determine the …