Aortic dissection (AD) is a fatal disease that accounts for a large proportion of aortic-related
deaths and has an incidence of about 3–4 per 100,000 individuals every year. Recent …

Heritable thoracic aortic aneurysms and dissections (TAAD), including Marfan syndrome
(MFS), currently lack a cure, and causative mutations have been identified for only a fraction …

Acute lung injury (ALI) and oxygenation impairment (OI) frequently occur in the patients with
acute aortic dissection (AAD), which may necessitate mechanical ventilation and result in …

Aims Thoracic aortic aneurysm/dissection (TAAD) is a life-threatening disease with diverse
clinical manifestations. Although the association between methamphetamine (METH) and …

Acute aortic dissection (AAD) is a life-threatening disease. Despite the higher risk of
mortality, currently there are no effective therapies that can ameliorate AAD development or …

MicroRNAs (miRNAs) packaged into exosomes mediate cell communication and contribute
to the pathogenesis of acute type A aortic dissection (ATAAD) with acute lung injury (ALI) …

Apelin has been proved to be a critical mediator of vascular function and homeostasis. Here,
we investigated roles of Apelin in aortic remodeling and fibrosis in rats with transverse aortic …

Astragalin, a bioactive component of medicinal plants such as Rosa agrestis, has anti-
inflammatory and antioxidant features. Induction of heme oxygenase (HO)-1 is an effective …

OBJECTIVE: To examine the expression of interleukin-6 (IL-6), interferon-γ (IFN-γ), smooth
muscle 22α (SM22α), and matrix metalloproteinase-2 (MMP-2) and their possible roles in …

The renin-angiotensin system (RAS), composed mainly of renin, angiotensin, and
aldosterone, is a key endocrine pathway involved in cardiovascular activity regulation …