[HTML][HTML] Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities
Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies
This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …
Cannabinoid receptors: An update on cell signaling, pathophysiological roles and therapeutic opportunities in neurological, cardiovascular, and inflammatory …
The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …
has been one of the most significant biochemical and pharmacological advancements to …
The molecular logic of endocannabinoid signalling
D Piomelli - Nature Reviews Neuroscience, 2003 - nature.com
The endocannabinoids are a family of lipid messengers that engage the cell surface
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …
[HTML][HTML] A second endogenous cannabinoid that modulates long-term potentiation
Cannabinoid receptors are molecular targets for marijuana and hashish, the widespread
drugs of abuse. These receptors are expressed in areas of the central nervous system that …
drugs of abuse. These receptors are expressed in areas of the central nervous system that …
[HTML][HTML] Role of endogenous cannabinoids in synaptic signaling
TF Freund, I Katona, D Piomelli - Physiological reviews, 2003 - journals.physiology.org
Freund, Tamás F., István Katona, and Daniele Piomelli. Role of Endogenous Cannabinoids
in Synaptic Signaling. Physiol Rev 83: 1017–1066, 2003; 10.1152/physrev. 00004.2003 …
in Synaptic Signaling. Physiol Rev 83: 1017–1066, 2003; 10.1152/physrev. 00004.2003 …
CB1 cannabinoid receptors and on-demand defense against excitotoxicity
G Marsicano, S Goodenough, K Monory, H Hermann… - Science, 2003 - science.org
Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons
from the consequences of abnormal discharge activity have been postulated. We generated …
from the consequences of abnormal discharge activity have been postulated. We generated …
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
S Weggen, JL Eriksen, P Das, SA Sagi, R Wang… - Nature, 2001 - nature.com
Epidemiological studies have documented a reduced prevalence of Alzheimer's disease
among users of nonsteroidal anti-inflammatory drugs (NSAIDs),,,,. It has been proposed that …
among users of nonsteroidal anti-inflammatory drugs (NSAIDs),,,,. It has been proposed that …
Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action
The existence of an endogenous cannabinoid system was demonstrated conclusively with
the discovery of endogenous brain constituents capable of activating the cannabinoid …
the discovery of endogenous brain constituents capable of activating the cannabinoid …
Endocannabinoid-mediated synaptic plasticity in the CNS
V Chevaleyre, KA Takahashi, PE Castillo - Annu. Rev. Neurosci., 2006 - annualreviews.org
Abstract Changes in synaptic efficacy are thought to be crucial to experience-dependent
modifications of neural function. The diversity of mechanisms underlying these changes is …
modifications of neural function. The diversity of mechanisms underlying these changes is …