Alterations in cardiac energy metabolism contribute to the severity of heart failure. However, the energy metabolic changes that occur in heart failure are complex and are dependent not …
Abstract The 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment was created to provide a practical, streamlined resource for clinicians …
G Hindricks, T Potpara, N Dagres, E Arbelo… - European heart …, 2021 - academic.oup.com
MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …
MAB Khan, MJ Hashim, H Mustafa, MY Baniyas… - Cureus, 2020 - cureus.com
Background Ischemic heart disease (IHD) is a leading cause of death worldwide. Also referred to as coronary artery disease (CAD) and atherosclerotic cardiovascular disease …
Abstract Background Coronary Artery Disease (CAD) is the foremost single cause of mortality and loss of Disability Adjusted Life Years (DALYs) globally. A large percentage of …
Feature attributions based on the Shapley value are popular for explaining machine learning models. However, their estimation is complex from both theoretical and …
CD Maida, RL Norrito, M Daidone… - International journal of …, 2020 - mdpi.com
One of the most important causes of neurological morbidity and mortality in the world is ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …
BR Stockwell, X Jiang, W Gu - Trends in cell biology, 2020 - cell.com
Cell death is an essential feature of development in multicellular organisms, a critical driver of degenerative diseases, and can be harnessed for treating some cancers. Understanding …
Tree-based machine learning models such as random forests, decision trees and gradient boosted trees are popular nonlinear predictive models, yet comparatively little attention has …