With the frequent occurrence of heatwaves, heatstroke (HS) is expected to become one of
the main causes of global death. Being a multi-organized disease, HS can result in …

Abstract Long-Covid (LC), Post-Sepsis-Syndrome (PSS) and Post-Intensive-Care-Syndrome
(PICS) show remarkable overlaps in their clinical presentation. Nevertheless, it is unclear if …

Background Klebsiella pneumoniae is infamous for hospital-acquired infections and sepsis,
which have also been linked to Alzheimer disease (AD)-related neuroinflammatory and …

Gut microbiota is an intricate microbial community containing bacteria, fungi, viruses,
archaea, and protozoa, and each of them contributes to diverse aspects of host health …

Sepsis is a state of systemic immune dysregulation and organ failure that is frequently
associated with severe brain disability. Epidemiological studies have indicated that younger …

Traumatic brain injury (TBI) is a chronic and debilitating disease, associated with a high risk
of psychiatric and neurodegenerative diseases. Despite significant advancements in …

Background Gut microbiota is closely related to the occurrence and development of sepsis.
However, the causal effects between the gut microbiota and sepsis, and whether circulating …

Objective: To evaluate the persistence of intestinal microbiome dysbiosis and gut-plasma
metabolomic perturbations following severe trauma or sepsis weeks after admission in …

Background Exposure to trauma is often associated with an increased incidence of Major
Depressive Disorder (MDD), yet the mechanisms underlying MDD development post-trauma …

脓毒症是一种异质性疾病, 抗生素和器官支持等传统治疗在改善患者预后方面存在诸多挑战.
近年来的研究表明肠道菌群不仅在脓毒症的发生和发展中扮演重要角色, 还在维持免疫稳态中起 …