Recent advances in 8π electrocyclization reactions

L Liu, L Du, B Li - Chemical Communications, 2023 - pubs.rsc.org
Medium-ring systems, which constitute a class of structurally intriguing and biologically
important molecules, are present in many natural products and pharmaceuticals. However …

Oxadiazolines as Photoreleasable Labels for Drug Target Identification

C Bon, B Goretzki, M Flamme, C Shelton… - Journal of the …, 2024 - ACS Publications
Photoaffinity labeling is a widely used technique for studying ligand–protein and protein–
protein interactions. Traditional photoaffinity labels utilize nonspecific C–H bond insertion …

Carrier Protein Mediated Formation of the Dihydropyridazinone Ring in Actinopyridazinone Biosynthesis

K Arima, S Akiyama, K Shin‐ya, K Matsuda… - Angewandte …, 2023 - Wiley Online Library
Heterocycles with nitrogen‐nitrogen (N− N) bonds are privileged building blocks of synthetic
drugs. They are also found in natural products, although the biosynthetic logic behind them …

The seven-step, one-pot regioselective synthesis of biologically important 3-aryllawsones: scope and applications

AV Krishna, DB Ramachary - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
3-Aryllawsones are well known for their wide range of applications in medicinal chemistry,
but their synthesis has always remained challenging as no comprehensive protocol has …

Six-membered ring systems: Diazines and benzo derivatives

KA Rinderspacher - Progress in Heterocyclic Chemistry, 2023 - Elsevier
In 2022 several major advances were made in the exploration of the chemistry of diazines
and their benzo derivatives. These compounds continue to find use as building blocks for …