The practice of polypharmacology is not a new concept but the approaches which are being
adopted for administering the two or more drugs together are varied from time to time …

Furanone, a five-membered heteroaromatic ring containing oxygen atom, is of immense
pharmaceutical importance. Presence of this nucleus in biologically active compounds of …

Currently, the available antifungal agents have significant clinical incompetency in terms of
their clinical efficacy, antifungal spectrum, unfavorable pharmacokinetic profiles, substantial …

The corrosion inhibition of API 5 L X52 in 1 M HCl due to fluconazole as active substance 1
or drug (Afungil), and its fragments: 1, 2, 4-triazole 2 and 1-bromo-2, 4-difluorobenzene 3 …

Herein, we report the design, synthesis and evaluation of a novel series of diselenide and
selenide derivatives as potent antifungal agents by exploiting the hydrophobic cleft of …

This review provides a comprehensive survey of proprietary drug discovery and
development efforts performed by Indian companies between 1994 and mid‐2016. It is …

A series of new dithiocarbamates containing a 2 (5H)-furanone-piperazine group was
synthesized. These compounds show good in vitro cytoxic activity. Among them, compound …

Aiming to obtain the more effective pathogen inhibitive ingredients and explore the influence
of introducing different heterocyclic units to carvacrol and thymol esters, twenty ester …

Hybrid molecule approach of drug design has become popular due to advantages such as
delayed resistance, reduced toxicity, ease of treatment of co-infection and lower cost of …

The important physicochemical properties of three novel bioactive hybrid compounds with
different groups (-CH3,-F and-Cl) were studied, including kinetic and thermodynamic …