In recent decades, mass spectrometry has moved more than ever before into the front line of
protein-centered research. After being established at the qualitative level, the more …

Highlights•Ideal mass spectrometer for MALDI MSI would satisfy the '4S-criteria for
performance'(speed, specificity, spatial resolution and sensitivity).•Quantification MALDI MSI …

Mass spectrometry imaging (MSI) is a powerful, label-free technique that provides detailed
maps of hundreds of molecules in complex samples with high sensitivity and subcellular …

Spatial metabolomics is an emerging field of omics research that has enabled localizing
metabolites, lipids, and drugs in tissue sections, a feat considered impossible just two …

Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is a fast-
growing technique for visualization of the spatial distribution of the small molecular and …

Significant advances in mass spectrometry imaging (MSI) have pushed the boundaries in
obtaining spatial information and quantification in biological samples. Quantitative MSI …

Covering: 2017 to 2022 Mass spectrometry imaging (MSI) has become a mature molecular
imaging technique that is well-matched for natural product (NP) discovery. Here we present …

New mass spectrometry imaging (MSI) techniques are gaining importance in various stages
of the drug discovery and development chain as well as in more fundamental studies of drug …

Molecular imaging has the potential to unearth important spatial and temporal relationships
in biological systems, including intercellular signaling as well as environmentally-cued …

Mass spectrometry imaging (MSI) has become a widespread analytical technique to perform
nonlabeled spatial molecular identification. The Achilles' heel of MSI is the annotation and …