[HTML][HTML] Regulation of Skeletal Development and Maintenance by Runx2 and Sp7
T Komori - International Journal of Molecular Sciences, 2024 - mdpi.com
Runx2 (runt related transcription factor 2) and Sp7 (Sp7 transcription factor 7) are crucial
transcription factors for bone development. The cotranscription factor Cbfb (core binding …
transcription factors for bone development. The cotranscription factor Cbfb (core binding …
[HTML][HTML] Roles of Sp7 in osteoblasts for the proliferation, differentiation, and osteocyte process formation
Q Jiang, K Nagano, T Moriishi, H Komori… - Journal of Orthopaedic …, 2024 - Elsevier
Background Zinc finger-containing transcription factor Osterix/Specificity protein-7 (Sp7) is
an essential transcription factor for osteoblast differentiation. However, its functions in …
an essential transcription factor for osteoblast differentiation. However, its functions in …
Metabolic regulation by biomaterials in osteoblast
Z Kang, B Wu, L Zhang, X Liang, D Guo… - … in Bioengineering and …, 2023 - frontiersin.org
The repair of bone defects resulting from high-energy trauma, infection, or pathological
fracture remains a challenge in the field of medicine. The development of biomaterials …
fracture remains a challenge in the field of medicine. The development of biomaterials …
Unveiling the Osteogenic Potential of Tetracyclines: A Comparative Study in Human Mesenchymal Stem Cells
V Martin, AF Bettencourt, C Santos, MH Fernandes… - Cells, 2023 - mdpi.com
Tetracyclines (TCs) are a class of broad-spectrum antibiotics with diverse
pharmacotherapeutic properties due to their various functional groups being attached to a …
pharmacotherapeutic properties due to their various functional groups being attached to a …
[HTML][HTML] Morinda officinalis polysaccharide boosts osteogenic differentiation of bone marrow mesenchymal stem cells by Wnt/β-catenin signaling
M Lai, X Chen, J Feng, Z Ruan… - American journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Objectives: To investigate the role of Morinda officinalis polysaccharide (MOP) in the protein
expression of the Wnt/β-catenin signaling cascade during the osteogenic differentiation of …
expression of the Wnt/β-catenin signaling cascade during the osteogenic differentiation of …
Bone Material Properties in Bone Diseases Affecting Children
Abstract Purpose of Review Metabolic and genetic bone disorders affect not only bone mass
but often also the bone material, including degree of mineralization, matrix organization, and …
but often also the bone material, including degree of mineralization, matrix organization, and …
Methylglyoxal compromises callus mineralization and impairs fracture healing through suppression of osteoblast terminal differentiation
T Seto, K Yukata, S Tsuji, Y Takeshima, T Honda… - Biochemical and …, 2025 - Elsevier
Impaired fracture healing in diabetic patients leads to prolonged morbidity and increased
healthcare costs. Methylglyoxal (MG), a reactive metabolite elevated in diabetes, is …
healthcare costs. Methylglyoxal (MG), a reactive metabolite elevated in diabetes, is …
Roles of SP/KLF transcription factors in odontoblast differentiation: From development to diseases
X Wang, K Sun, Z Xu, Z Chen, W Wu - Oral Diseases, 2024 - Wiley Online Library
Objectives A zinc‐finger transcription factor family comprising specificity proteins (SPs) and
Krüppel‐like factor proteins (KLFs) plays an important role in dentin development and …
Krüppel‐like factor proteins (KLFs) plays an important role in dentin development and …
Long-term follow-up of severe autosomal recessive SP7-related bone disorder
LW Gauthier, E Fontanges, R Chapurlat, C Collet… - Bone, 2024 - Elsevier
The SP7 gene encodes a zinc finger transcription factor (Osterix), which is a member of the
Sp subfamily of sequence-specific DNA-binding proteins, playing an important role in …
Sp subfamily of sequence-specific DNA-binding proteins, playing an important role in …
他汀类药物与骨密度: 一项药物靶向孟德尔随机化分析
马玮玮， 熊勇， 陈虹谷， 黄文茁， 黄新， 周晓红 - 中国组织工程研究, 2024 - cjter.com
他汀类药物与骨密度:一项药物靶向孟德尔随机化分析 Page 1 4340|中国组织工程研究|第28卷|第
27期|2024年9月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …
27期|2024年9月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …