Gout is the most common inflammatory arthritis and occurs when hyperuricaemia, sustained
elevation of serum urate levels resulting in supersaturation of body tissues with urate, leads …

Gout is a picturesque presentation of uric acid disturbance. It is the most well understood
and described type of arthritis. Its epidemiology is studied. New insights into the …

Objective To provide guidance for the management of gout, including indications for and
optimal use of urate‐lowering therapy (ULT), treatment of gout flares, and lifestyle and other …

Serum uric acid (SUA) is significantly elevated in obesity, gout, type 2 diabetes mellitus, and
the metabolic syndrome and appears to contribute to the renal, cardiovascular and …

Gout is the most common form of inflammatory arthritis and is a multifactorial disease
typically characterized by hyperuricemia and monosodium urate crystal deposition …

Purine metabolism in the circulatory system yields uric acid as its final oxidation product,
which is believed to be linked to the development of gout and kidney stones. Hyperuricemia …

This review article summarizes the relevant English literature on gout from 2010 through
April 2017. It emphasizes that the current epidemiology of gout indicates a rising prevalence …

This article aims to critically review the evidence on the available therapeutic strategies for
the treatment of hyperuricemia. For this reason, several papers were reviewed. Xanthine …

Objectives Determine the efficacy and safety of daily lesinurad (200 or 400 mg orally) added
to allopurinol in patients with serum uric acid (sUA) above target in a 12-month, randomised …

Gout and chronic kidney disease (CKD) frequently coexist, but quality evidence to guide
gout management in people with CKD is lacking. Use of urate-lowering therapy (ULT) in the …