The heart is the first functional organ in a developing embryo. Cardiac development
continues throughout developmental stages while the heart goes through a serious of …

The increasing prevalence of heart disease poses a significant threat to human survival and
safety. However, the current treatments available for heart disease are quite limited …

Coordinated cell movement is a fundamental process in organ formation. During heart
development, bilateral myocardial precursors collectively move toward the midline (cardiac …

Background Cardiovascular system is saddled with responsibility of pumping blood into
circulation, thereby providing nourishment to tissues and removal of metabolic wastes …

Inborn errors of metabolism cause abnormal synthesis, recycling, or breakdown of amino
acids, neurotransmitters, and other various metabolites. This aberrant homeostasis …

Abstract Purpose of Review Congenital heart disease includes a wide variety of structural
cardiac defects, the most severe of which are single ventricle defects (SVD). These patients …

Zebrafish (Danio rerio) have become indispensable models for advancing our
understanding of multiple metabolic disorders such as obesity, diabetes mellitus …

In this study, we propose a new method for bioprinting 3D Spheroids to study complex
congenital heart disease known as discrete subaortic stenosis (DSS). The bioprinter allows …

Visualizing dynamic cellular behaviors using live imaging is critical to the study of cell
movement and to the study of cellular and embryonic polarity. Similarly, live imaging can be …

Coordinated cell movement is a fundamental process in organ formation. During heart
development, bilateral myocardial precursors collectively move towards the midline (cardiac …