A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

SZ Bahojb Mahdavi, A Jebelli… - Medicinal research …, 2024 - Wiley Online Library
Infections caused by viruses as the smallest infectious agents, pose a major threat to global
public health. Viral infections utilize different host mechanisms to facilitate their own …

Respiratory viral infections in exacerbation of chronic airway inflammatory diseases: novel mechanisms and insights from the upper airway epithelium

KS Tan, RL Lim, J Liu, HH Ong, VJ Tan… - Frontiers in cell and …, 2020 - frontiersin.org
Respiratory virus infection is one of the major sources of exacerbation of chronic airway
inflammatory diseases. These exacerbations are associated with high morbidity and even …

SARS-CoV-2 infection remodels the phenotype and promotes angiogenesis of primary human lung endothelial cells

F Caccuri, A Bugatti, A Zani, A De Palma, D Di Silvestre… - Microorganisms, 2021 - mdpi.com
SARS-CoV-2-associated acute respiratory distress syndrome (ARDS) and acute lung injury
are life-threatening manifestations of severe viral infection. The pathogenic mechanisms that …

Rationale for the role of heparin and related GAG antithrombotics in COVID-19 infection

HN Magnani - Clinical and Applied Thrombosis/Hemostasis, 2021 - journals.sagepub.com
The SARS-CoV-2 pandemic has focused attention on prevention, restriction and treatment
methods that are acceptable worldwide. This means that they should be simple and …

Annexin A1 as a potential prognostic biomarker for COVID‐19 disease: Case–control study

O Canacik, R Sabirli, E Altintas, E Karsli… - … journal of clinical …, 2021 - Wiley Online Library
Abstract Background Annexin A1 (AnxA1) is an important endogenous glucocoticoid protein
that contributes to the suppression of inflammation by limiting the production of neutrophil …

Unravelling the immunomodulatory effects of viral ion channels, towards the treatment of disease

S Gargan, NJ Stevenson - Viruses, 2021 - mdpi.com
The current COVID-19 pandemic has highlighted the need for the research community to
develop a better understanding of viruses, in particular their modes of infection and …

FMDV 3A antagonizes the effect of ANXA1 to positively modulate viral replication

XS Ma, KS Zhang, ZK Luo, XF Nian… - Journal of …, 2022 - Am Soc Microbiol
The RIG-I-like receptor signaling pathway is crucial for producing type I interferon (IFN-I)
against RNA viruses. The present study observed that viral infection increased annexin-A1 …

Predictive Value of Annenxin A1 for Disease Severity and Prognosis in Patients with Community-Acquired Pneumonia

M Gu, X Han, X Liu, F Sui, Q Zhang, S Pan - Diagnostics, 2023 - mdpi.com
This prospective, single-center study evaluated the clinical utility of annenxin (Anx) A1 level
as a biomarker for determining the severity of illness and predicting the risk of death in …

[HTML][HTML] Characterization and proteome profiling of extracellular vesicles in a murine model of Staphylococcus aureus endophthalmitis

D Rudraprasad, MV Sushma, AK Rengan, MN Naik… - Microbes and …, 2022 - Elsevier
Endophthalmitis is a vision-threatening complication of intraocular surgery or penetrating
injury of which Staphylococcus aureus is an important etiological agent. Extracellular …

GENIX enables comparative network analysis of single-cell RNA sequencing to reveal signatures of therapeutic interventions

N Nouri, G Gaglia, H Mattoo, E de Rinaldis… - Cell Reports Methods, 2024 - cell.com
Single-cell RNA sequencing (scRNA-seq) has transformed our understanding of cellular
responses to perturbations such as therapeutic interventions and vaccines. Gene relevance …