Intestinal mucus forms the first line of defense against bacterial invasion while providing
nutrition to support microbial symbiosis. How the host controls mucus barrier integrity and …

Knowledge of the Michaelis–Menten parameters and their meaning in different
circumstances is an essential prerequisite to understanding enzyme function and behaviour …

This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Nucleotide sugars (NSs) serve as substrates for glycosylation reactions. The majority of
these compounds are synthesized in the cytoplasm, whereas glycosylation occurs in the …

Idiopathic pulmonary fibrosis (IPF) is a disease characterized by progressive scarring of the
lung that involves the pulmonary interstitium. The disease may rapidly progress, leading to …

In mammalian cells, SLC35A2 delivers UDP–galactose for galactosylation reactions that
take place predominantly in the Golgi lumen. Mutations in the corresponding gene cause a …

Congenital disorders of glycosylation (CDG) are a group of rare genetic and metabolic
diseases caused by alterations in glycosylation pathways. Five patients bearing CDG …

Abstract Beta 1, 4‐galactosyltransferase (B4GALT)‐family glycosyltransferases are involved
in multiple biological processes promoting cancer progression, regulating the dynamic …

The sialylation of glycoconjugates is performed by a variety of sialyltransferases using CMP-
sialic acid (CMP-Sia) as a substrate. Sialylation requires the translocation of CMP-Sia …

Nucleotide sugar transporters (NSTs) are multitransmembrane proteins, localized in the
Golgi apparatus and/or endoplasmic reticulum, which provide glycosylation enzymes with …