Lab-on-a-chip technologies for the single cell level: Separation, analysis, and diagnostics

A Hochstetter - Micromachines, 2020 - mdpi.com
In the last three decades, microfluidics and its applications have been on an exponential
rise, including approaches to isolate rare cells and diagnose diseases on the single-cell …

Global BioID-based SARS-CoV-2 proteins proximal interactome unveils novel ties between viral polypeptides and host factors involved in multiple COVID19 …

EMN Laurent, Y Sofianatos, A Komarova, JP Gimeno… - BioRxiv, 2020 - biorxiv.org
The worldwide SARS-CoV-2 outbreak poses a serious challenge to human societies and
economies. SARS-CoV-2 proteins orchestrate complex pathogenic mechanisms that …

[HTML][HTML] Insights of Novel Coronavirus (SARS-CoV-2) disease outbreak, management and treatment

D Kumar, L Batra, MT Malik - AIMS microbiology, 2020 - ncbi.nlm.nih.gov
Emerging and re-emerging viral diseases poses a threat to living organisms, and led to
serious concern to humankind and public health. The last two decades, viral epidemics such …

Atypical divergence of SARS-CoV-2 Orf8 from Orf7a within the coronavirus lineage suggests potential stealthy viral strategies in immune evasion

RY Neches, NC Kyrpides, CA Ouzounis - MBio, 2021 - Am Soc Microbiol
Orf8, one of the most puzzling genes in the SARS lineage of coronaviruses, marks a unique
and striking difference in genome organization between SARS-CoV-2 and SARS-CoV-1 …

Diversity in the accessory proteins of SARS-CoV-2, SARS-CoV, and MERS-CoV Betacoronaviruses

CAK Cruz, PMB Medina - Current Protein and Peptide Science, 2021 - benthamdirect.com
Along with structural and non-structural proteins, SARS-CoV-2, SARS-CoV, and MERS-CoV
can also express accessory proteins. During the past few years, there have been only a few …

Molecular dynamic simulation of intrinsically disordered proteins and relevant forcefields

P Kumar, N Sharma, A Kumar, R Giri - Innovations and Implementations of …, 2021 - Springer
Intrinsically disordered proteins (IDPs) exist in every form of life, from bacteria to humans
and viruses. They do not hold any well-defined or properly folded structure in the …

[PDF][PDF] Tuning intrinsic disorder predictors for virus proteins

G Almog, AS Olabode, AFY Poon - Virus Evolution, 2021 - academic.oup.com
Many virus-encoded proteins have intrinsically disordered regions that lack a stable, folded
three-dimensional structure. These disordered proteins often play important functional roles …