Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has been responsible for a devastating pandemic since March …

Recognition of viral infection by pattern recognition receptors is paramount for a successful
immune response to viral infection. However, an unbalanced proinflammatory response can …

COVID-19 is linked to endotheliopathy and coagulopathy, which can result in multi-organ
failure. The mechanisms causing endothelial damage due to severe acute respiratory …

Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

Background As a consequence of SARS-CoV-2 infection various neurocognitive and
neuropsychiatric symptoms can appear, which may persist for several months post infection …

Clinical evidence reveals that manifestations of endothelial dysfunction are widely observed
in COVID-19 and long-COVID patients. However, whether these detrimental effects are …

Background In post-coronavirus disease-19 (post-COVID-19) conditions (long COVID),
systemic vascular dysfunction is implicated, but the mechanisms are uncertain, and the …

Eugenol as a natural product is the source of isoniazid, and purified eugenol is extensively
used in the cosmetics industry and the productive processes of edible spices. Accumulating …

Dexamethasone (DEX) is a potent synthetic glucocorticoid used for the treatment of variety
of inflammatory and immune-mediated disorders. The RECOVERY clinical trial revealed …

SARS-CoV-2 provokes devastating tissue damage by cytokine release syndrome and leads
to multi-organ failure. Modeling the process of immune cell activation and subsequent tissue …