The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …

Peripheral neuropathies account for the most frequent disorders seen by neurologists, and
causes are manifold. The traditional diagnostic gold-standard consists of clinical neurologic …

Aims/hypothesis The individual risk of progression of diabetic peripheral neuropathy is
difficult to predict for each individual. Mutations in proteins that are responsible for the …

Background Diabetic peripheral neuropathy (DPN) has been shown to be independently
associated with cardiovascular events and mortality. This study aimed to evaluate changes …

Background Nerve damage in diabetic neuropathy (DN) is assumed to begin in the distal
legs with a subsequent progression to hands and arms at later stages. In contrast, recent …

Diabetic neuropathic pain (DNP) is a diabetes complication experienced by many patients.
Ventrolateral periaqueductal gray (vlPAG) neurons are essential mediators of the …

Clinical studies have suggested that changes in peripheral nerve microcirculation may
contribute to nerve damage in diabetic polyneuropathy (DN). High-sensitivity troponin T …

Objectives Clinical and histological studies have found evidence that nerve ischemia is a
major contributor to diabetic neuropathy (DN) in type 2 diabetes (T2D). The aim of this study …

Peripheral nerve injuries (PNIs) continue to present both diagnostic and treatment
challenges. While nerve transections are typically a straightforward diagnosis, other types of …

Diabetic neuropathy (DPN) is one of the most severe and yet most poorly understood
complications of diabetes mellitus. In vivo imaging of dorsal root ganglia (DRG), a key …