The emergence of spatial multi-omics has helped address the limitations of single-cell
sequencing, which often leads to the loss of spatial context among cell populations …

Metabolomics has made significant progress in multiple fronts in the last 18 months. This
minireview aimed to give an overview of these advancements in the light of their contribution …

Nuclear magnetic resonance (NMR) spectroscopy is an important analytical technique in
metabolomics. Because it provides atomic-level detail of small molecules, NMR is …

Metabolomics holds great promise for uncovering insights around biological processes
impacting disease in human epidemiological studies. Metabolites can be measured across …

Pleiotropy and genetic correlation are widespread features in genome-wide association
studies (GWAS), but they are often difficult to interpret at the molecular level. Here, we …

Despite the crucial roles of lipids in metabolism, we are still at the early stages of
comprehensively annotating lipid species and their genetic basis. Mass spectrometry–based …

Background Metabolomics is the comprehensive study of a multitude of small molecules to
gain insight into an organism's metabolism. The research field is dynamic and expanding …

Metabolites are small molecules that are intermediates or products of metabolism, many of
which are freely filtered by the kidneys. In addition, the kidneys have a central role in …

Crohn's disease (CD) is characterised by chronic inflammation. We aimed to identify a
relationship between plasma inflammatory metabolomic signature and genomic data in CD …

Bioactive fatty acid-derived oxylipin molecules play key roles mediating inflammation and
oxidative stress. Circulating levels of fatty acids and oxylipins are influenced by …