Ca2+-release channels are giant membrane proteins that control the release of Ca2+ from
the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors …

Ion channels play a central role in the regulation of nearly every cellular process. Dating
back to the classic 1952 Hodgkin–Huxley model of the generation of the action potential, ion …

The ryanodine receptors (RyRs) are high-conductance intracellular Ca2+ channels that play
a pivotal role in the excitation–contraction coupling of skeletal and cardiac muscles. RyRs …

Ryanodine receptors (RyRs) are located in the sarcoplasmic/endoplasmic reticulum
membrane and are responsible for the release of Ca2+ from intracellular stores during …

Large-conductance Ca2+ release channels known as ryanodine receptors (RyRs) mediate
the release of Ca2+ from an intracellular membrane compartment, the endo/sarcoplasmic …

Cryoelectron microscopy of biological molecules is among the hottest growth areas in
biophysics and structural biology at present, and Frank is arguably the most distinguished …

The ryanodine receptors (RyRs) are a family of Ca2+ release channels found on
intracellular Ca2+ storage/release organelles. The RyR channels are ubiquitously …

Ion channels are membrane proteins that act as gated pathways for the movement of ions
across cell membranes. They play essential roles in the physiology of all cells. In recent …

Ryanodine receptors (RyRs) are a distinct class of ligand-gated calcium channels
controlling the release of calcium from intracellular stores. They are located on the …

The ryanodine receptor (RyR) is a high-conductance Ca2+ channel of the sarcoplasmic
reticulum in muscle and of the endoplasmic reticulum in other cells. In striated muscle fibers …