The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …

Endurance exercise-mediated multisystemic adaptations are known to mitigate metabolism-
related disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the …

Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

Two opposing models have been proposed to describe the function of the MYC oncoprotein
in shaping cellular transcriptomes: one posits that MYC amplifies transcription at all active …

The RNA exosome complex is the most versatile RNA-degradation machine in eukaryotes.
The exosome has a central role in several aspects of RNA biogenesis, including RNA …

The eukaryotic RNA exosome is an essential and conserved protein complex that can
degrade or process RNA substrates in the 3′-to-5′ direction. Since its discovery nearly …

Objective Wound healing remains a challenge in burns and trauma fields. Adipose derived
stem cells exosomes (AD-exos) had been confirmed to have a positive effect on the wound …

Habitual endurance exercise training is associated with multisystemic metabolic adaptations
that lower the risk of inactivity-associated disorders such as obesity and type 2 diabetes …

The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …

Mitochondrial structural and functional integrity is maintained through the coordination of
several processes (eg, biogenesis, dynamics, mitophagy), collectively referred to as …