The biology of mucus: Composition, synthesis and organization

R Bansil, BS Turner - Advanced drug delivery reviews, 2018 - Elsevier
In this review we discuss mucus, the viscoelastic secretion from goblet or mucous producing
cells that lines the epithelial surfaces of all organs exposed to the external world. Mucus is a …

Bacterial hydrodynamics

E Lauga - Annual Review of Fluid Mechanics, 2016 - annualreviews.org
Bacteria predate plants and animals by billions of years. Today, they are the world's smallest
cells, yet they represent the bulk of the world's biomass and the main reservoir of nutrients …

Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review

A Sosnik, J das Neves, B Sarmento - Progress in Polymer Science, 2014 - Elsevier
The presence of a mucus layer that covers the surface of a variety of organs has been
capitalized to develop mucoadhesive dosage forms that remain in the administration site for …

Mucus-inspired dynamic hydrogels: Synthesis and future perspectives

R Bej, R Haag - Journal of the American Chemical Society, 2022 - ACS Publications
Mucus hydrogels at biointerfaces are crucial for protecting against foreign pathogens and for
the biological functions of the underlying cells. Since mucus can bind to and host both …

Mucins and their role in shaping the functions of mucus barriers

CE Wagner, KM Wheeler… - Annual review of cell and …, 2018 - annualreviews.org
We review what is currently understood about how the structure of the primary solid
component of mucus, the glycoprotein mucin, gives rise to the mechanical and biochemical …

Staying in shape: the impact of cell shape on bacterial survival in diverse environments

DC Yang, KM Blair, NR Salama - Microbiology and Molecular …, 2016 - Am Soc Microbiol
Bacteria display an abundance of cellular forms and can change shape during their life
cycle. Many plausible models regarding the functional significance of cell morphology have …

Microswimming in viscoelastic fluids

G Li, E Lauga, AM Ardekani - Journal of Non-Newtonian Fluid Mechanics, 2021 - Elsevier
The locomotion of microorganisms and spermatozoa in complex viscoelastic fluids is of
critical importance in many biological processes such as fertilization, infection, and biofilm …

Mucus models to evaluate the diffusion of drugs and particles

JY Lock, TL Carlson, RL Carrier - Advanced drug delivery reviews, 2018 - Elsevier
Mucus is a complex hydrogel that acts as a natural barrier to drug delivery at different
mucosal surfaces including the respiratory, gastrointestinal, and vaginal tracts. To elucidate …

Role of Flagella in the Pathogenesis of Helicobacter pylori

H Gu - Current microbiology, 2017 - Springer
This review aimed to investigate the role of Helicobacter pylori flagella on the pathogenicity
of this bacterium in humans. Helicobacter pylori is a flagellated pathogen that colonizes the …

A rheological study of the association and dynamics of MUC5AC gels

CE Wagner, BS Turner, M Rubinstein… - …, 2017 - ACS Publications
The details of how a mucus hydrogel forms from its primary structural component, mucin
polymers, remain incompletely resolved. To explore this, we use a combination of …