Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …

Major depressive disorder (MDD) was previously hypothesized to be a disease of
monoamine deficiency in which low levels of monoamines in the synaptic cleft were …

Immature dentate granule cells (imGCs) arising from adult hippocampal neurogenesis
contribute to plasticity and unique brain functions in rodents, and are dysregulated in …

Disrupted hippocampal performance underlies psychiatric comorbidities and cognitive
impairments in patients with neurodegenerative disorders. To understand the contribution of …

Hippocampus is the significant component of the limbic lobe, which is further subdivided into
the dentate gyrus and parts of Cornu Ammonis. It is the crucial region for learning and …

Some recent clinical and preclinical evidence suggests that neuroinflammation is a key
factor that interacts with the three neurobiological correlates of major depressive disorder …

The hippocampus is one of the most affected areas in Alzheimer's disease (AD) 1. Moreover,
this structure hosts one of the most unique phenomena of the adult mammalian brain …

Insulin plays a range of roles as an anabolic hormone in peripheral tissues. It regulates
glucose metabolism, stimulates glucose transport into cells and suppresses hepatic glucose …

The rodent hippocampus generates new neurons throughout life. This process, named adult
hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the …

Neural stem cells (NSCs) generate new neurons throughout life in the mammalian brain.
Adult-born neurons shape brain function, and endogenous NSCs could potentially be …