Abstract Background Coronaviruses (CoVs) primarily cause enzootic infections in birds and
mammals but, in the last few decades, have shown to be capable of infecting humans as …

Monocarboxylates such as lactate and pyruvate play a central role in cellular metabolism
and metabolic communication between tissues. Essential to these roles is their rapid …

Bacterial conjugation is the fundamental process of unidirectional transfer of DNAs, often
plasmid DNAs, from a donor cell to a recipient cell. It is the primary means by which …

Background Until now, polymyxin resistance has involved chromosomal mutations but has
never been reported via horizontal gene transfer. During a routine surveillance project on …

RNA interference (RNAi) has been recognized as a novel and safe strategy in pest
management due to its high sequence-dependent specificity. However, the existing dsRNA …

Recently, we reported the discovery of three novel coronaviruses, bulbul coronavirus
HKU11, thrush coronavirus HKU12, and munia coronavirus HKU13, which were identified …

The colonization of land by plants was a key event in the evolution of life. Here we report the
draft genome sequence of the filamentous terrestrial alga Klebsormidium flaccidum (Division …

Antigen identification is an important step in the vaccine development process.
Computational approaches including deep learning systems can play an important role in …

The inflammasome is an intracellular signaling complex, which on recognition of pathogens
and physiological aberration, drives activation of caspase-1, pyroptosis, and the release of …

Microbiota-modulating interventions are an emerging strategy to promote gastrointestinal
homeostasis. Yet, their use in the detection, prevention, and treatment of acute infections …