A large body of literature supports the idea that inflammation plays a pivotal role in all
phases of atherosclerosis, from the fatty streak lesion formation to the acute coronary event …

In recent years, it has become increasingly clear that arterial inflammation represents a key
feature determining the course of atherogenesis. The consecutive stages in the evolution of …

Endothelial cells play a critical role in inflammation by responding to several endogenous
and exogenous proinflammatory stimuli. The three most studied factors that provide …

Activation of the complement system can induce and enhance inflammatory reaction.
Mannose-binding lectin-associated serine protease-1 (MASP-1) is an abundant protease of …

Pathologically increased vascular permeability is an important dysfunction in the
pathomechanism of life-threatening conditions, such as sepsis, ischemia/reperfusion, or …

Endothelial cells play an important role in sensing danger signals and regulating
inflammation. Several factors are capable of inducing a proinflammatory response (eg, LPS …

Background Formation of haemorrhagic neovessels in the intima of developing
atherosclerotic plaques is thought to significantly contribute to plaque instability resulting in …

Microbial infection urges prompt intervention by the immune system. The complement
cascade and neutrophil granulocytes are the predominant contributors to this immediate anti …

Selective capturing and purification of C-reactive protein (CRP) from complex biological
fluids plays a pivotal role in studying biological activities of CRP in various diseases …

The complement system and neutrophil granulocytes are indispensable in the immune
response against extracellular pathogens such as bacteria and fungi. Endothelial cells also …