The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex
multi-cellular organ that intimately links with the cardiovascular system to accomplish gas …

Tissue engineering and regenerative medicine have shown potential in the repair and
regeneration of tissues and organs via the use of engineered biomaterials and scaffolds …

The native extracellular matrix (ECM) outlines the architecture of organs and tissues. It
provides a unique niche of composition and form, which serves as a foundational scaffold …

End-stage renal failure is a devastating disease, with donor organ transplantation as the
only functional restorative treatment. The current number of donor organs meets less than …

In view of their low immunogenicity, biomimetic internal environment, tissue-and organ-like
physicochemical properties, and functionalization potential, decellularized extracellular …

With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for
organ engineering were generated from numerous tissues, including the heart, lung, liver …

Background Organ engineering is a theoretical alternative to allotransplantation for end-
stage organ failure. Whole-organ scaffolds can be created by detergent perfusion via the …

Background The only definitive treatment for end-stage organ failure is orthotopic
transplantation. Lung extracellular matrix (LECM) holds great potential as a scaffold for lung …

Organ transplantation is the most effective therapy for patients with end-stage disease.
Preservation solutions and techniques are crucial for donor organ quality, which is directly …

Hydrogels derived from decellularized lungs are promising materials for tissue engineering
in the development of clinical therapies and for modeling the lung extracellular matrix (ECM) …