Nanobiotechnology approaches for cardiovascular diseases: site-specific targeting of drugs and nanoparticles for atherothrombosis

H Liu, G Pietersz, K Peter, X Wang - Journal of Nanobiotechnology, 2022 - Springer
Atherosclerosis and atherothrombosis, the major contributors to cardiovascular diseases
(CVDs), represent the leading cause of death worldwide. Current pharmacological therapies …

Near-infrared light-responsive liposomes for protein delivery: Towards bleeding-free photothermally-assisted thrombolysis

A Refaat, B Del Rosal, J Palasubramaniam… - Journal of Controlled …, 2021 - Elsevier
Smart drug delivery systems represent state-of-the-art approaches for targeted therapy of life-
threatening diseases such as cancer and cardiovascular diseases. Stimuli-responsive on …

“ISCHEMIC STROKE: From Fibrinolysis to Functional Recovery” Nanomedicine: emerging approaches to treat ischemic stroke

P Sarfati, T De La Taille, C Portioli, R Spanò… - Neuroscience, 2024 - Elsevier
Stroke is responsible for 11% of all deaths worldwide, the majority of which are caused by
ischemic strokes, thus making the need to urgently find safe and effective therapies. Today …

Ultrasound-propelled janus rod-shaped micromotors for site-specific sonodynamic thrombolysis

W Cao, Y Liu, P Ran, J He, S Xie… - ACS Applied Materials …, 2021 - ACS Publications
Antithrombosis therapy is confronted with short half-lives of thrombolytic agents, limited
therapeutic effects, and bleeding complications. Drug delivery systems of thrombolytic …

Drug delivery under cover of erythrocytes extends drug half-life: A thrombolytic targeting therapy utilizing microenvironment-responsive artificial polysaccharide …

L Shan, J Wang, H Tu, W Zhang, H Li, P Slezak… - Carbohydrate …, 2024 - Elsevier
The development of thrombolytic drug carriers capable of thrombus-targeting, prolonged
circulation time, intelligent responsive release, and the ability to inhibit thrombotic …

Ultrasound-powered hydrogen peroxide-responsive Janus micromotors for targeted thrombolysis and recurrence inhibition

W Cao, W Wei, B Qiu, Y Liu, S Xie, Q Fang… - Chemical Engineering …, 2024 - Elsevier
Thrombosis seriously endangers human health with high incidence and mortality worldwide,
and the clinical treatment is challenged by low bioavailability of thrombolytic agents, high …

[HTML][HTML] Shape memory alloy helical microrobots with transformable capability towards vascular occlusion treatment

H Zhang, B Xu, Y Ouyang, Y Wang, H Zhu, G Huang… - Research, 2022 - spj.science.org
Practical implementation of minimally invasive biomedical applications has been a long-
sought goal for microrobots. In this field, most previous studies only demonstrate microrobots …

Crafting Iron Oxides for Next-Generation Biomedical Applications

T Amrillah, BA Notodidjojo, M Kalimanjaro… - Crystal Growth & …, 2024 - ACS Publications
Iron oxides are multifunctional materials that have been extensively explored for many
applications, including in novel biomedical applications. However, boosting their ability for …

Targeting Nanomotor with Near‐Infrared/Ultrasound Triggered‐Transformation for Polystage‐Propelled Cascade Thrombolysis and Multimodal Imaging Diagnosis

R Ruan, S Chen, J Su, N Liu, H Feng… - Advanced …, 2024 - Wiley Online Library
Nowadays, cardiovascular and cerebrovascular diseases caused by venous
thromboembolism become main causes of mortality around the world. The current …

Bioactive Metal–Organic Frameworks as a Distinctive Platform to Diagnosis and Treat Vascular Diseases

W Liu, Y Li, Y Wang, Y Feng - Small, 2024 - Wiley Online Library
Vascular diseases (VDs) pose the leading threat worldwide due to high morbidity and
mortality. The detection of VDs is commonly dependent on individual signs, which limits the …