Iron acquisition strategies in pseudomonads: mechanisms, ecology, and evolution

R Kümmerli - Biometals, 2023 - Springer
Iron is important for bacterial growth and survival, as it is a common co-factor in essential
enzymes. Although iron is very abundant in the earth crust, its bioavailability is low in most …

Adaptation to novel spatially-structured environments is driven by the capsule and alters virulence-associated traits

A Nucci, EPC Rocha, O Rendueles - Nature Communications, 2022 - nature.com
The extracellular capsule is a major virulence factor, but its ubiquity in free-living bacteria
with large environmental breadths suggests that it shapes adaptation to novel niches. Yet …

Experimental evolution of yeast shows that public-goods upregulation can evolve despite challenges from exploitative non-producers

RJ Lindsay, PJ Holder, M Hewlett, I Gudelj - Nature Communications, 2024 - nature.com
Microbial secretions, such as metabolic enzymes, are often considered to be cooperative
public goods as they are costly to produce but can be exploited by others. They create …

Adaptation to an amoeba host leads to Pseudomonas aeruginosa isolates with attenuated virulence

W Leong, WH Poh, J Williams, C Lutz… - Applied and …, 2022 - Am Soc Microbiol
The opportunistic pathogen Pseudomonas aeruginosa is ubiquitous in the environment, and
in humans, it is capable of causing acute or chronic infections. In the natural environment …

Phenotypic heterogeneity unveils a negative correlation between antibiotic resistance and quorum sensing in Pseudomonas aeruginosa clinical isolates

X Yang, Q Zeng, S Gou, Y Wu, X Ma, H Zou… - Frontiers in …, 2024 - frontiersin.org
Colonization of Pseudomonas aeruginosa in the lung environments frequently leads to the
enrichment of strains displaying enhanced antibiotic resistance and reduced production of …

Evolution of Quorum Sensing in Pseudomonas aeruginosa Can Occur via Loss of Function and Regulon Modulation

P Jayakumar, ART Figueiredo, R Kümmerli - Msystems, 2022 - Am Soc Microbiol
Pseudomonas aeruginosa populations evolving in cystic fibrosis lungs, animal hosts, natural
environments and in vitro undergo extensive genetic adaption and diversification. A …

[HTML][HTML] Recombination as an enforcement mechanism of prosocial behavior in cooperating bacteria

IPA Lee, OT Eldakar, JP Gogarten, CP Andam - Iscience, 2023 - cell.com
Prosocial behavior is ubiquitous in nature despite the relative fitness costs carried by
cooperative individuals. However, the stability of cooperation in populations is fragile and …

Community composition drives siderophore dynamics in multispecies bacterial communities

S O'Brien, CT Culbert, TG Barraclough - BMC Ecology and Evolution, 2023 - Springer
Background Intraspecific public goods are commonly shared within microbial populations,
where the benefits of public goods are largely limited to closely related conspecifics. One …

Copper selects for siderophore-mediated virulence in Pseudomonas aeruginosa

L Lear, E Hesse, A Buckling, M Vos - BMC microbiology, 2022 - Springer
Background Iron is essential for almost all bacterial pathogens and consequently it is
actively withheld by their hosts. However, the production of extracellular siderophores …

Evolution of Cooperation in Spatio-Temporal Evolutionary Games with Public Goods Feedback

H Cheng, L Sysoeva, H Wang, H Yuan, T Zhang… - Bulletin of Mathematical …, 2024 - Springer
In biology, evolutionary game-theoretical models often arise in which players' strategies
impact the state of the environment, driving feedback between strategy and the …