Long-term effects of severe burns on the kidneys: research advances and potential therapeutic approaches

G Yang, L Tan, H Yao, Z Xiong, J Wu… - Journal of Inflammation …, 2023 - Taylor & Francis
Burns are a seriously underestimated form of trauma that not only damage the skin system
but also cause various complications, such as acute kidney injury (AKI). Recent clinical …

The proximal tubule as the pathogenic and therapeutic target in acute kidney injury

KM Ho, DJR Morgan - Nephron, 2022 - karger.com
Background: In 2004, the term acute kidney injury (AKI) was introduced with the intention of
broadening our understanding of rapid declines in renal function and to replace the …

Polystyrene nanoplastics alter the cytotoxicity of human pharmaceuticals on marine fish cell lines

M Almeida, MA Martins, AMV Soares, A Cuesta… - Environmental …, 2019 - Elsevier
There is an increasing concern on the consequences of the presence of micro (nano)
plastics to marine organisms. The present study aimed to provide information on the effects …

The effect of low-dose furosemide in critically ill patients with early acute kidney injury: a pilot randomized blinded controlled trial (the SPARK study)

SM Bagshaw, RTN Gibney, P Kruger, I Hassan… - Journal of critical …, 2017 - Elsevier
Purpose Furosemide is commonly prescribed in acute kidney injury (AKI). Prior studies have
found conflicting findings on whether furosemide modifies the course and outcome of AKI …

Blood–urea–nitrogen-to-serum–albumin ratio in predicting the value of patients with contrast-induced nephropathy for coronary heart disease

Q Pan, Y Peng, H Ni, L Lin, B Luo, X Huang… - … Urology and Nephrology, 2024 - Springer
Background The blood–urea–nitrogen (BUN)-to-serum–albumin (ALB) ratio (BAR) has been
identified as a novel indicator of both inflammatory and nutritional status, exhibiting a …

Early diuretic use and mortality in critically ill patients with vasopressor support: a propensity score-matching analysis

Y Shen, W Zhang, Y Shen - Critical Care, 2019 - Springer
Background The effect of loop diuretic use in critically ill patients on vasopressor support or
in shock is unclear. This study aimed to explore the relationship between loop diuretic use …

Impact of furosemide on mortality and the requirement for renal replacement therapy in acute kidney injury: a systematic review and meta-analysis of randomised trials

ŁJ Krzych, PF Czempik - Annals of Intensive Care, 2019 - Springer
Objective To examine the impact of furosemide on mortality and the need for renal
replacement therapy (RRT) in adult patients with acute kidney injury (AKI) based on current …

Furosemide reverses medullary tissue hypoxia in ovine septic acute kidney injury

N Iguchi, YR Lankadeva, TA Mori… - American Journal …, 2019 - journals.physiology.org
In experimental sepsis, the rapid development of renal medullary hypoxia precedes the
development of acute kidney injury (AKI) and may contribute to its pathogenesis. We …

Hospitalized patients received furosemide undergoing acute kidney injury: the risk and prediction tool

C Guan, C Li, L Xu, L Che, Y Wang, C Yang… - European Journal of …, 2023 - Springer
Purpose Furosemide, a frequently prescribed diuretic for managing congestive heart failure
and edema, remains a topic of debate regarding its potential risk of inducing acute kidney …

Effect of furosemide on urinary oxygenation in patients with septic shock

EA Osawa, SL Cutuli, L Bitker, E Canet, L Cioccari… - Blood purification, 2019 - karger.com
Background: Renal medullary hypoxia precedes the development of acute kidney injury in
experimental sepsis and can now be assessed by continuous measurement of urinary …