Exploitation of plasmin (ogen) by bacterial pathogens of veterinary significance

BBA Raymond, S Djordjevic - Veterinary microbiology, 2015 - Elsevier
The plasminogen (Plg) system plays an important homeostatic role in the degradation of
fibrin clots, extracellular matrices and tissue barriers important for cellular migration, as well …

Mycoplasma hyopneumoniae resides intracellularly within porcine epithelial cells

BBA Raymond, L Turnbull, C Jenkins, R Madhkoor… - Scientific reports, 2018 - nature.com
Enzootic pneumonia incurs major economic losses to pork production globally. The primary
pathogen and causative agent, Mycoplasma hyopneumoniae, colonises ciliated epithelium …

Cytokine expression and Mycoplasma hyopneumoniae burden in the development of lung lesions in experimentally inoculated pigs

HMS Almeida, ML Mechler-Dreibi, K Sonálio… - Veterinary …, 2020 - Elsevier
This study aimed to assess immunopathological factors and M. hyopneumoniae (M. hyo)
load in macroscopic lesion formation at four timepoints after experimental infection of swine …

Evaluation of clinical, histological and immunological changes and qPCR detection of Mycoplasma hyopneumoniae in tissues during the early stages of mycoplasmal …

LK Woolley, S Fell, JR Gonsalves, MJ Walker… - Veterinary …, 2012 - Elsevier
Differences in Mycoplasma hyopneumoniae strain virulence and infection patterns will affect
experimental challenge systems used to evaluate vaccine efficacy. Two strains (Hillcrest and …

Local and systemic immune responses in pigs intramuscularly injected with an inactivated Mycoplasma hyopneumoniae vaccine

SB Marchioro, D Maes, B Flahou, F Pasmans… - Vaccine, 2013 - Elsevier
The immune response induced by intramuscular administration of a commercial inactivated
Mycoplasma hyopneumonie whole-cell vaccine (Suvaxyn® MH One) was investigated in …

Intra-species and inter-species differences in cytokine production by porcine antigen-presenting cells stimulated by Mycoplasma hyopneumoniae, M. hyorhinis, and M …

S Fourour, C Marois-Créhan, L Martelet, C Fablet… - Pathogens, 2019 - mdpi.com
Mycoplasma hyorhinis and M. flocculare are commonly co-isolated with M. hyopneumoniae
(primary agent of swine enzootic pneumonia) in gross pneumonia-like lesions, but their …

Histopathological and immunohistochemical findings in the lungs of pigs infected experimentally with Mycoplasma hyopneumoniae

E Redondo, AJ Masot, A Fernández… - Journal of comparative …, 2009 - Elsevier
Pigs were infected intranasally with Mycoplasma hyopneumoniae and killed at intervals
ranging from 7 to 35 days post-infection (dpi). Histopathological changes consisted of (1) …

Interactions of highly and low virulent Mycoplasma hyopneumoniae isolates with the respiratory tract of pigs

T Meyns, D Maes, D Calus, S Ribbens, J Dewulf… - Veterinary …, 2007 - Elsevier
Mycoplasma hyopneumoniae is the etiological agent of swine enzootic pneumonia, a
chronic nonfatal disease affecting pigs of all ages. To obtain better insight in the …

Evaluation of recombinant Mycoplasma hyopneumoniae P97/P102 paralogs formulated with selected adjuvants as vaccines against mycoplasmal pneumonia in pigs

LK Woolley, SA Fell, JR Gonsalves, BBA Raymond… - Vaccine, 2014 - Elsevier
Pig responses to recombinant subunit vaccines containing fragments of eight multifunctional
adhesins of the Mycoplasma hyopneumoniae (Mhp) P97/P102 paralog family formulated …

Mycoplasma hyopneumoniae induces pro-inflammatory cytokine and nitric oxide production through NFκB and MAPK pathways in RAW264.7 cells

MH Hwang, D Damte, JS Lee, E Gebru… - Veterinary research …, 2011 - Springer
In the present study, we confirmed the ability of M. hyopneumoniae to induce the secretion of
large amount of proinflammatory cytokine and nitric oxide (NO) in murine macrophage RAW …