Artificial intelligence for brain diseases: A systematic review

A Segato, A Marzullo, F Calimeri, E De Momi - APL bioengineering, 2020 - pubs.aip.org
Artificial intelligence (AI) is a major branch of computer science that is fruitfully used for
analyzing complex medical data and extracting meaningful relationships in datasets, for …

Quantitative approaches to guide epilepsy surgery from intracranial EEG

JM Bernabei, A Li, AY Revell, RJ Smith… - Brain, 2023 - academic.oup.com
Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

Evidence of a large current of transcranial alternating current stimulation directly to deep brain regions

Y Shan, H Wang, Y Yang, J Wang, W Zhao… - Molecular …, 2023 - nature.com
Deep brain regions such as hippocampus, insula, and amygdala are involved in
neuropsychiatric disorders, including chronic insomnia and depression. Our recent reports …

The interictal suppression hypothesis in focal epilepsy: network-level supporting evidence

GW Johnson, DJ Doss, VL Morgan, DL Paulo, LY Cai… - Brain, 2023 - academic.oup.com
Why are people with focal epilepsy not continuously having seizures? Previous neuronal
signalling work has implicated gamma-aminobutyric acid balance as integral to seizure …

A multi-scale cortical wiring space links cellular architecture and functional dynamics in the human brain

C Paquola, J Seidlitz, O Benkarim, J Royer… - PLoS …, 2020 - journals.plos.org
The vast net of fibres within and underneath the cortex is optimised to support the
convergence of different levels of brain organisation. Here, we propose a novel coordinate …

NREM sleep is the state of vigilance that best identifies the epileptogenic zone in the interictal electroencephalogram

P Klimes, J Cimbalnik, M Brazdil, J Hall, F Dubeau… - …, 2019 - Wiley Online Library
Objective Interictal epileptiform anomalies such as epileptiform discharges or high‐
frequency oscillations show marked variations across the sleep‐wake cycle. This study …

Interictal high‐frequency oscillations, spikes, and connectivity profiles: A fingerprint of epileptogenic brain pathologies

B Sklenárová, E Zatloukalova, J Cimbálník… - …, 2023 - Wiley Online Library
Objective Focal cortical dysplasia (FCD), hippocampal sclerosis (HS), nonspecific gliosis
(NG), and normal tissue (NT) comprise the majority of histopathological results of surgically …

Generalisability of epileptiform patterns across time and patients

H Karimi-Rouzbahani, A McGonigal - Scientific Reports, 2024 - nature.com
The complexity of localising the epileptogenic zone (EZ) contributes to surgical resection
failures in achieving seizure freedom. The distinct patterns of epileptiform activity during …

Relative entropy is an easy‐to‐use invasive electroencephalographic biomarker of the epileptogenic zone

V Travnicek, P Klimes, J Cimbalnik, J Halamek… - …, 2023 - Wiley Online Library
Objective High‐frequency oscillations are considered among the most promising interictal
biomarkers of the epileptogenic zone in patients suffering from pharmacoresistant focal …

Artificial intelligence in epilepsy—applications and pathways to the clinic

A Lucas, A Revell, KA Davis - Nature Reviews Neurology, 2024 - nature.com
Artificial intelligence (AI) is rapidly transforming health care, and its applications in epilepsy
have increased exponentially over the past decade. Integration of AI into epilepsy …