Thirst motivates animals to find and consume water. More than 40 years ago, a set of
interconnected brain structures known as the lamina terminalis was shown to govern thirst …

OVER the past few years, considerable evidence has accumulated to challenge the
accepted view of the regulation of adrenocortical function. Conventionally, the cortex and …

A syndrome is described whose features, suggestive of primary mineralocorticoid excess,
included hypertension, hypokalemia, low PRA, and responsiveness to spironolactone …

Methods We studied seven normal volunteers and eleven pa-tients with cirrhosis. The
diagnosis of cirrhosis was de-termined from pertinent findings of the history and physical …

We would like to take this opportunity of expressing our sincerest thanks to the many
persons who have made adrenal tissue and related materials available to us for our work …

Publisher Summary This chapter reviews the historical perspective into the conceptual
evolution of 11β-hydroxysteroid dehydrogenase (HSD) from its pedestrian origin as an …

Aldosterone exerts profound effects on renal and cardiovascular physiology. In the kidney,
aldosterone acts to preserve electrolyte and acid-base balance in response to changes in …

Adrenal cells have been prepared, using crude collagenase, from the separated capsular
and decapsulated portions of adrenals from intact rats. Microscopic examination and …

The peripheral plasma levels of aldosterone, renin activity (PRA), potassium, corticosterone,
cortisol, and in some cases angiotensin II, were measured in normal subjects undergoing …

Prevalence, pathogenesis, and functional significance of aldoste-rone deficiency in
hyperkalemic patients with chronic renal in-sufficiency. Plasma and urinary aldosterone …