Self-emulsifying drug delivery systems (SEDDS) are a proven method for poorly soluble
substances works by increasing the solubility and bioavailability. SEDDS and isotropic …

At present, the majority of APIs synthesized today remain challenging tasks for formulation
development. Many technologies are being utilized or explored for enhancing solubility …

In present investigation, we developed paclitaxel (PTX)-loaded adenosine (ADN)-
conjugated PLGA nanoparticles for combating triple-negative breast cancer (TNBC), where …

Understanding the mechanisms underlying the dispersion and digestion process is vital in
the development of oral lipid-based formulations (LBFs). In vitro lipolysis models mimic the …

Understanding and controlling the drug solubilization in digestive environment is of great
importance in the design of lipid based solid dispersion (LBSD) for oral delivery of poorly …

Multiple sclerosis (MS) is a complex autoimmune disorder of the central nervous system
(CNS) which causes various symptoms such as fatigue, dyscoordination weakness and …

A gradual loss of neuronal function or structure causes neurodegenerative disorders such
as Parkinson's and Alzheimer's. Neurological damage might cause cell death. Acrolein is a …

Lipid-based formulations (LbFs) have demonstrated success in pharmaceutical applications;
however, challenges persist in dissolving entire doses of the drug into defined liquid …

Self-emulsification is considered a formulation technique that has proven capacity to
improve oral drug delivery of poorly soluble drugs by advancing both solubility and …

Self-emulsifying drug delivery systems (SEDDS) represent an innovative approach to
improving the solubility and bioavailability of poorly water-soluble drugs, addressing …