CA125 and ovarian cancer: a comprehensive review

P Charkhchi, C Cybulski, J Gronwald, FO Wong… - Cancers, 2020 - mdpi.com
Simple Summary CA125 has been the most promising biomarker for screening ovarian
cancer; however, it still does not have an acceptable accuracy in population-based …

Molecular biomarkers for the early detection of ovarian cancer

R Zhang, MKY Siu, HYS Ngan, KKL Chan - International Journal of …, 2022 - mdpi.com
Ovarian cancer is the deadliest gynecological cancer, leading to over 152,000 deaths each
year. A late diagnosis is the primary factor causing a poor prognosis of ovarian cancer and …

Current and emerging methods for ovarian cancer screening and diagnostics: a comprehensive review

JM Liberto, SY Chen, IM Shih, TH Wang, TL Wang… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Advances in mass spectrometry-based clinical biomarker discovery

CA Crutchfield, SN Thomas, LJ Sokoll, DW Chan - Clinical proteomics, 2016 - Springer
The greatest unmet needs in biomarker discovery are those discoveries that lead to the
development of clinical diagnostic tests. These clinical diagnostic tests can provide early …

Personalized proteomics: the future of precision medicine

TT Duarte, CT Spencer - Proteomes, 2016 - mdpi.com
Medical diagnostics and treatment has advanced from a one size fits all science to treatment
of the patient as a unique individual. Currently, this is limited solely to genetic analysis …

[HTML][HTML] Validation of a second-generation multivariate index assay for malignancy risk of adnexal masses

RL Coleman, TJ Herzog, DW Chan, DG Munroe… - American journal of …, 2016 - Elsevier
Background Women with adnexal mass suspected of ovarian malignancy are likely to
benefit from consultation with a gynecologic oncologist, but imaging and biomarker tools to …

[HTML][HTML] In 2014, can we do better than CA125 in the early detection of ovarian cancer?

JG Cohen, M White, A Cruz… - World journal of …, 2014 - ncbi.nlm.nih.gov
Ovarian cancer is a lethal gynecologic malignancy with greater than 70% of women
presenting with advanced stage disease. Despite new treatments, long term outcomes have …

Guideline no. 403: initial investigation and management of adnexal masses

S Salvador, S Scott, P Glanc, L Eiriksson… - Journal of Obstetrics and …, 2020 - Elsevier
Objectives To aid primary care physicians, emergency medicine physicians, and
gynaecologists in the initial investigation of adnexal masses, defined as lumps that appear …

Quantitative global lipidomics analysis of patients with ovarian cancer versus benign adnexal mass

MF Buas, CW Drescher, N Urban, CI Li, L Bettcher… - Scientific reports, 2021 - nature.com
Altered lipid metabolism has emerged as an important feature of ovarian cancer (OC), yet
the translational potential of lipid metabolites to aid in diagnosis and triage remains …

Identification of novel candidate plasma metabolite biomarkers for distinguishing serous ovarian carcinoma and benign serous ovarian tumors

MF Buas, H Gu, D Djukovic, J Zhu, CW Drescher… - Gynecologic …, 2016 - Elsevier
Objective Serous ovarian carcinoma (OC) represents a leading cause of cancer-related
death among US women. Non-invasive tools have recently emerged for discriminating …