Adverse cutaneous toxicities by PD-1/PD-L1 immune checkpoint inhibitors: pathogenesis, treatment, and surveillance

M Bhardwaj, MN Chiu… - Cutaneous and ocular …, 2022 - Taylor & Francis
Introduction The therapeutic use of humanised monoclonal programmed cell death 1 (PD-
1)(pembrolizumab, and nivolumab) and programmed cell death ligand-1 (PD …

[HTML][HTML] Dermatologic immune-related adverse events: The toxicity spectrum and recommendations for management

Z Apalla, B Rapoport, V Sibaud - International journal of women's …, 2021 - Elsevier
Immune checkpoint inhibitors are a new class of oncologic drugs that act via the inhibition of
checkpoints, thereby unlocking the immune system to attack cancer cells. Their emergence …

European recommendations for management of immune checkpoint inhibitors‐derived dermatologic adverse events. The EADV task force 'Dermatology for cancer …

Z Apalla, V Nikolaou, D Fattore… - Journal of the …, 2022 - Wiley Online Library
The introduction of immune checkpoint inhibitors (ICIs) opened a new era in oncologic
therapy. The favourable profile of ICIs in terms of efficacy and safety can be overshadowed …

Treatment of advanced melanoma: Past, present and future

T Fujimura, Y Kambayashi, K Ohuchi, Y Muto, S Aiba - Life, 2020 - mdpi.com
Therapeutic options for treating advanced melanoma are progressing rapidly. Until six years
ago, the regimen for treating advanced melanoma mainly comprised cytotoxic agents such …

Severe de novo pustular psoriasiform immune‐related adverse event associated with nivolumab treatment for metastatic esophageal adenocarcinoma

RNH Seervai, M Heberton, WC Cho… - Journal of cutaneous …, 2022 - Wiley Online Library
Breakthrough targeted therapies have produced significant improvements in survival for
cancer patients, but have a propensity to cause cutaneous immune‐related adverse events …

Immune Checkpoint Inhibitor-Induced Psoriasis: Diagnosis, Management, and a Review of Cases

JJ Pach, N Mbonu, S Bhullar, JM Cohen… - Dermatologic …, 2024 - derm.theclinics.com
Immune checkpoint inhibitors (ICIs) have transformed the treatment of cancer. ICIs enhance
antitumor activity by relieving inhibition of T cells responsible for immune surveillance and …

Immune checkpoint inhibitor-induced cutaneous toxicities: a review of histopathologic and clinical features

J Martel, HL Hanania, AB Patel - Human Pathology, 2023 - Elsevier
Immune checkpoint inhibitors (ICIs) represent an emerging treatment option for a variety of
cancer types. Through inhibition of programmed cell death protein 1 (PD-1), programmed …

Perspectives on Psoriasiform Adverse Events from Immune Checkpoint Inhibitors: Lessons Learned from Our Practice

LG Popa, C Giurcaneanu, MG Portelli, MM Mihai… - Medicina, 2024 - mdpi.com
Background: New oncologic therapies, including immune checkpoint inhibitors (ICIs), have
revolutionized the survival and prognosis of cancer patients. However, these therapies are …

[HTML][HTML] Exacerbation of psoriasis induced by Nivolumab in a patient with stage IIIc gastric adenocarcinoma: A case report and literature review

X Sun, X Mei, Y Liu - Journal of Translational Autoimmunity, 2023 - Elsevier
Nivolumab, the programmed cell death 1 inhibitor, is a kind of immune checkpoint inhibitor
commonly used to treat advanced cancers. Unfortunately, such drugs often induce various …

Medical dilemma: Programmed death 1 blockade (sintilimab) therapy in patients suffering from tumours combined with psoriasis

D Jin, YW Wang, ZM Lin, C Li… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Tumour immunotherapy represented by immune checkpoint inhibitors (ICIs) has greatly
improved the overall prognosis of patients with malignant tumours, and is regarded as an …