Human cardiac metabolism

MR Bornstein, R Tian, Z Arany - Cell Metabolism, 2024 - cell.com
The heart is the most metabolically active organ in the human body, and cardiac metabolism
has been studied for decades. However, the bulk of studies have focused on animal models …

Can nutrition contribute to a reduction in sarcopenia, frailty, and comorbidities in a super-aged society?

S Yoshida, R Shiraishi, Y Nakayama, Y Taira - Nutrients, 2023 - mdpi.com
Many countries are facing the advent of super-aging societies, where sarcopenia and frailty
will become pertinent problems. The prevalence of comorbidities is a major problem in …

[HTML][HTML] Coenzyme Q10 as adjunctive therapy for cardiovascular disease and hypertension: a systematic review

CB Sue-Ling, WM Abel, K Sue-Ling - The Journal of Nutrition, 2022 - Elsevier
Background Mitochondrial ATP production requires a small electron carrier, coenzyme Q 10
(CoQ 10), which has been used as adjunctive therapy in patients with cardiovascular …

Effect of coenzyme Q10 on cardiac function and survival in heart failure: an overview of systematic reviews and meta-analyses

E Alarcón-Vieco, I Martínez-García… - Food & Function, 2023 - pubs.rsc.org
Heart failure (HF) is associated with a deficiency in blood levels of coenzyme Q10 (CoQ10),
and its supplementation has been proposed. The aim of this systematic review was to …

Mitochondrial dysfunction in heart failure and its therapeutic implications

M Liu, J Lv, Z Pan, D Wang, L Zhao… - Frontiers in …, 2022 - frontiersin.org
The ATP consumption in heart is very intensive to support muscle contraction and relaxation.
Mitochondrion is the power plant of the cell. Mitochondrial dysfunction has long been …

[HTML][HTML] Modulation of the nitric oxide/cGMP pathway in cardiac contraction and relaxation: Potential role in heart failure treatment

R Mollace, F Scarano, I Bava, C Carresi… - Pharmacological …, 2023 - Elsevier
Evidence exists that heart failure (HF) has an overall impact of 1-2% in the global population
being often associated with comorbidities that contribute to increased disease prevalence …

Efficacy of antioxidant supplementation in improving endocrine, hormonal, inflammatory, and metabolic statuses of PCOS: a meta-analysis and systematic review

J He, R Deng, Y Wei, S Zhang, M Su, M Tang… - Food & Function, 2024 - pubs.rsc.org
Background and aim: A large number of recent studies have reported on the use of
antioxidants in patients with polycystic ovary syndrome (PCOS). This study aimed to …

Cardioprotective role of the coenzyme Q10 and coconut oil in acute aluminum phosphide poisoning: a randomized controlled clinical trial

RE Elsharkawy, MM Ghonem… - Toxicology …, 2023 - academic.oup.com
Aluminum phosphide (ALP)-induced cardiotoxicity is a major cause of high mortality rates.
As there is no specific antidote, restoring cardiac hemodynamics is the cornerstone for …

Coenzyme Q10 Reduces Infarct Size in Animal Models of Myocardial Ischemia-Reperfusion Injury: A Meta-Analysis and Summary of Underlying Mechanisms

K Awad, A Sayed, M Banach - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
Objective Effective interventions that might limit myocardial ischemia-reperfusion (I/R) injury
are still lacking. Coenzyme Q10 (CoQ10) may exert cardioprotective actions that reduce …

Chronic heart failure in children: state of the art and new perspectives

B Castaldi, E Cuppini, J Fumanelli, A Di Candia… - Journal of Clinical …, 2023 - mdpi.com
Pediatric heart failure (HF) is an important clinical condition with high morbidity and
mortality. Compared to adults, pediatric HF shows different etiologies characterized by …