The complexity of piroplasms life cycles

M Jalovecka, O Hajdusek, D Sojka… - Frontiers in cellular …, 2018 - frontiersin.org
Although apicomplexan parasites of the group Piroplasmida represent commonly identified
global risks to both animals and humans, detailed knowledge of their life cycles is …

Approaches to vaccination against Theileria parva and Theileria annulata

V Nene, WI Morrison - Parasite Immunology, 2016 - Wiley Online Library
Despite having different cell tropism, the pathogenesis and immunobiology of the diseases
caused by Theileria parva and Theileria annulata are remarkably similar. Live vaccines …

Late-stage C–H alkylation of heterocycles and 1, 4-quinones via oxidative homolysis of 1, 4-dihydropyridines

Á Gutiérrez-Bonet, C Remeur, JK Matsui… - Journal of the …, 2017 - ACS Publications
Under oxidative conditions, 1, 4-dihydropyridines (DHPs) undergo a homolytic cleavage,
forming exclusively a Csp3-centered radical that can engage in the C–H alkylation of …

Host cell CRISPR genomics and modelling reveal shared metabolic vulnerabilities in the intracellular development of Plasmodium falciparum and related …

M Maurizio, M Masid, K Woods, R Caldelari… - Nature …, 2024 - nature.com
Parasitic diseases, particularly malaria (caused by Plasmodium falciparum) and theileriosis
(caused by Theileria spp.), profoundly impact global health and the socioeconomic well …

Towards a new phenotype for tick resistance in beef and dairy cattle: A review

HM Burrow, BJ Mans, FF Cardoso… - Animal Production …, 2019 - CSIRO Publishing
About 80% of the world's cattle are affected by ticks and tick-borne diseases, both of which
cause significant production losses. Cattle host resistance to ticks is the most important …

An appraisal of oriental theileriosis and the Theileria orientalis complex, with an emphasis on diagnosis and genetic characterisation

H Gebrekidan, PK Perera, A Ghafar, T Abbas… - Parasitology …, 2020 - Springer
Oriental theileriosis, a tick-borne disease of bovids caused by members of the Theileria
orientalis complex, has a worldwide distribution. Globally, at least 11 distinct genotypes of T …

Tick-borne pathogens and body condition of cattle in smallholder rural livestock production systems in East and West Africa

DJA Heylen, B Kumsa, E Kimbita, MN Frank… - Parasites & …, 2023 - Springer
Background The majority of the African population lives in rural areas where they heavily
depend on crop and livestock production for their livelihoods. Given their socio-economic …

Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential

KA Moser, EF Drábek, A Dwivedi, EM Stucke… - genome medicine, 2020 - Springer
Abstract Background Plasmodium falciparum (Pf) whole-organism sporozoite vaccines have
been shown to provide significant protection against controlled human malaria infection …

Interacting effects of land use and climate on rodent-borne pathogens in central Kenya

HS Young, DJ McCauley, R Dirzo… - … of the Royal …, 2017 - royalsocietypublishing.org
Understanding the effects of anthropogenic disturbance on zoonotic disease risk is both a
critical conservation objective and a public health priority. Here, we evaluate the effects of …

Diversity and Distribution of Theileria Species and Their Vectors in Ruminants from India, Pakistan and Bangladesh

J Zeb, B Song, MU Aziz, S Hussain, R Zarin… - Diversity, 2022 - mdpi.com
Tropical theileriosis, caused by the apicomplexan hemoparasite of the genus Theileria, is a
major constraint to livestock production in various parts of world, including South Asia …