[HTML][HTML] Expanding the function of oligodendrocytes to brain energy metabolism

KA Nave, E Asadollahi, A Sasmita - Current Opinion in Neurobiology, 2023 - Elsevier
Oligodendrocytes are best known for wrapping myelin, a unique specialization that enables
energy-efficient and fast axonal impulse propagation in white matter tracts and fibers of the …

Oligodendrocytes: myelination, plasticity, and axonal support

M Simons, EM Gibson, KA Nave - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The myelination of axons has evolved to enable fast and efficient transduction of electrical
signals in the vertebrate nervous system. Acting as an electric insulator, the myelin sheath is …

Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles

EM Krämer-Albers, HB Werner - Nature Reviews Neuroscience, 2023 - nature.com
Extracellular vesicles (EVs) have recently emerged as versatile elements of cell
communication in the nervous system, mediating tissue homeostasis. EVs influence the …

Tempol improves optic nerve histopathology and ultrastructures in cisplatin-induced optic neuropathy in rats by targeting oxidative stress—Endoplasmic reticulum …

AE Alsemeh, MAE Hulail, HEL Mokhtar… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Optic neuropathy is an affection of the optic neurons, which ends with blindness
and occurs either primarily due to direct affection of the optic nerve or secondarily as a …

Loss of the Novel Myelin Protein CMTM5 in Multiple Sclerosis Lesions and Its Involvement in Oligodendroglial Stress Responses

J Zhan, Y Gao, L Heinig, M Beecken, Y Huo, W Zhang… - Cells, 2023 - mdpi.com
This study comprehensively addresses the involvement of the protein CKLF-like Marvel
transmembrane domain-containing family member 5 (CMTM5) in the context of …

Role of chemokine-like factor 1 as an inflammatory marker in diseases

Y Li, H Yu, J Feng - Frontiers in Immunology, 2023 - frontiersin.org
Immunoinflammatory mechanisms have been incrementally found to be involved in the
pathogenesis of multiple diseases, with chemokines being the main drivers of immune cell …

Single-cell atlas of murine adrenal glands reveals immune-adrenal crosstalk during systemic Candida albicans infection

K Zhang, Y Hu, R Li, T Li - Frontiers in Immunology, 2022 - frontiersin.org
Fungal sepsis remains a major health threat with high mortality, where the adrenal gland
stress response has been rarely reported. Candida albicans (C. albicans) is the most …

SLC45A3 serves as a potential therapeutic biomarker to attenuate white matter injury after intracerebral hemorrhage

Y Zhang, H Zeng, F Lou, X Tan, X Zhang… - Translational Stroke …, 2024 - Springer
Intracerebral hemorrhage (ICH) is a severe cerebrovascular disease, which impairs patients'
white matter even after timely clinical interventions. Indicated by studies in the past decade …

Developmental maturation and regional heterogeneity but no sexual dimorphism of the murine CNS myelin proteome

SB Siems, VI Gargareta, LC Schadt… - Glia, 2025 - Wiley Online Library
The molecules that constitute myelin are critical for the integrity of axon/myelin‐units and
thus speed and precision of impulse propagation. In the CNS, the protein composition of …

Bioenergetics of Axon Integrity and Its Regulation by Oligodendrocytes and Schwann Cells

SK Mishra, SP Tiwari - Molecular Neurobiology, 2024 - Springer
Axons are long slender portions of neurons that transmit electrical impulses to maintain
proper physiological functioning. Axons in the central nervous system (CNS) and peripheral …