New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

During the last decades, male urogenital cancers (including prostate, renal, bladder and
testicular cancers) have become one of the most frequently encountered malignancies …

Abstract Background and Objective: Epigenetic alterations are common events in clear cell
renal cell carcinoma (ccRCC), and protein arginine methyltransferase 1 (PRMT1) is an …

Simple Summary Patients with triple-negative breast cancer (TNBC) respond well to
chemotherapy initially but are prone to relapse. Searching for new therapeutic targets, we …

Proper protein arginine methylation by protein arginine methyltransferase 1 (PRMT1) is
critical for maintaining cellular health, while dysregulation is often associated with disease …

The tyrosine kinase inhibitor sunitinib is an effective first-line treatment for patients with
advanced renal cell carcinoma (RCC). Hypothesizing that a functional read-out by mass …

Protein arginine methylation is a posttranslational modification catalyzed by the protein
arginine methyltransferase (PRMT) enzyme family. Dysregulated protein arginine …

Thyroid carcinoma (TC) represents the most prevalent malignancy of the endocrine system.
Protein arginine methyltransferase 1 (PRMT1) is a critical member of the protein arginine …

Renal cell carcinoma accounts for 2–3% of all cancers. It is difficult to diagnose early.
Recently, genome-wide studies have identified that histone methylation was one of the …

The methylation of arginine residues by protein arginine methyltransferases (PRMTs) is a
crucial post-translational modification for many biological processes, including DNA repair …